Dual-functionalized liposome by co-delivery of paclitaxel with sorafenib for synergistic antitumor efficacy and reversion of multidrug resistance
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery"
DOI: 10.1080/10717544.2019.1580797
Abstract: Abstract Multidrug resistance (MDR) remains one of the major reasons for inefficiency of many chemotherapeutic agents in cancer therapy. In this study, a D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) and polylysine-deoxycholic acid copolymer (PLL-DA) co-modified… read more here.
Keywords: mdr; delivery; delivery paclitaxel; multidrug resistance ... See more keywords
mPEG-Cholic acid/TPGS mixed micelles for combined delivery of paclitaxel and bufalin to treat hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical development and technology"
DOI: 10.1080/10837450.2022.2037140
Abstract: In this study, amphiphilic block copolymer mPEG-cholic acid was synthesized in conjunction with TPGS as stabilizer to prepare multifunctional micelles. The formed polymeric micelles (PCTm) were used for the delivery of paclitaxel (PTX) and bufalin… read more here.
Keywords: cholic acid; mpeg cholic; pctm; delivery paclitaxel ... See more keywords
LDL mediated delivery of Paclitaxel and MRI imaging probes for personalized medicine applications
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-021-00955-9
Abstract: Background The combination of imaging and therapeutic agents in the same smart nanoparticle is a promising option to perform a minimally invasive imaging guided therapy. In this study, Low density lipoproteins (LDL), one of the… read more here.
Keywords: medicine; delivery paclitaxel; ptx; ldl ... See more keywords