Engineered Curli Nanofilaments as a Self-Adjuvanted Antigen Delivery Platform.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300224
Abstract: Proteinaceous nanoparticles constitute efficient antigen delivery systems in vaccine formulations due to their size and repetitive nature that mimic most invading pathogens and promote immune activation. Nonetheless, the co-administration of an adjuvant with subunit nanovaccines… read more here.
Keywords: self adjuvanted; delivery platform; antigen; antigen delivery ... See more keywords
Nanosized zeolites as a gas delivery platform in a glioblastoma model.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120249
Abstract: Approaches able to counteract, at least temporarily, hypoxia, a well-known factor of resistance to treatment in solid tumors are highly desirable. Herein, we report the use of nanosized zeolite crystals as hyperoxic/hypercapnic gas carriers for… read more here.
Keywords: nanosized zeolites; gas; zeolites gas; delivery platform ... See more keywords
Liposomal doxorubicin as targeted delivery platform: Current trends in surface functionalization.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120117
Abstract: Liposomal delivery systems have significantly enhanced the efficacy and safety of chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are vesicles made up of lipophilic bilayer and a hydrophilic core which provides perfect opportunity for… read more here.
Keywords: delivery; doxorubicin targeted; delivery platform; doxorubicin ... See more keywords
Intracellular Delivery Platform for "Recalcitrant" Cells: When Polymeric Carrier Marries Photoporation.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b06201
Abstract: The intracellular delivery of exogenous macromolecules is of great interest for both fundamental biological research and clinical applications. Although traditional delivery systems based on either carrier mediation or membrane disruption have some advantages; however, they… read more here.
Keywords: delivery; delivery platform; carrier; platform recalcitrant ... See more keywords
pH/NIR-Responsive Polypyrrole-Functionalized Fibrous Localized Drug-Delivery Platform for Synergistic Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b17664
Abstract: Localized drug-delivery systems (LDDSs) are a promising approach for cancer treatment because they decrease systematic toxicity and enhance the therapeutic effect of the drugs via site-specific delivery of active compounds and possible gradual release. However,… read more here.
Keywords: drug delivery; delivery; ptx; drug ... See more keywords
Soft Nanohydrogels Based on Laponite Nanodiscs: A Versatile Drug Delivery Platform for Theranostics and Drug Cocktails.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b06149
Abstract: A new nanohydrogel drug delivery platform based on Laponite nanodiscs, polyacrylate, and sodium phosphate salts is described. The hybrid nanohydrogel is tailored to obtain soft and flexible nanohydrogels with G' around 3 kPa, which has… read more here.
Keywords: drug delivery; based laponite; delivery; drug ... See more keywords
Psychosocial work environment and mental wellbeing of food delivery platform workers in Helsinki, Finland: A qualitative study
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Qualitative Studies on Health and Well-being"
DOI: 10.1080/17482631.2023.2173336
Abstract: ABSTRACT Purpose Food delivery platform work is a relatively new phenomenon in Finland and has not been studied widely hence limited knowledge on its work environment. The aim of this study was to explore and… read more here.
Keywords: food delivery; work environment; delivery platform; work ... See more keywords
Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm1032
Abstract: Proinflammatory cytokines have been approved by the Food and Drug Administration for the treatment of metastatic melanoma and renal carcinoma. However, effective cytokine therapy requires high-dose infusions that can result in antidrug antibodies and/or systemic… read more here.
Keywords: delivery platform; cytokine delivery; translatable cytokine; clinically translatable ... See more keywords
Exosomes and mimics as novel delivery platform for cancer therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1001417
Abstract: Exosomes are nano-sized biological extracellular vesicles transmitting information between cells and constituting a new intercellular communication mode. Exosomes have many advantages as an ideal drug delivery nanocarrier, including good biocompatibility, permeability, low toxicity, and low… read more here.
Keywords: delivery platform; novel delivery; mimics novel; platform cancer ... See more keywords
Cyclosporine A Delivery Platform for Veterinary Ophthalmology—A New Concept for Advanced Ophthalmology
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101525
Abstract: Cyclosporine A (CsA) is a selective and reversible immunosuppressant agent that is widely used as a medication for a wide spectrum of diseases in humans such as graft versus host disease, non-infectious uveitis, rheumatoid arthritis,… read more here.
Keywords: delivery platform; veterinary ophthalmology; ophthalmology; cyclosporine ... See more keywords
An Innovative PTD-IVT-mRNA Delivery Platform for CAR Immunotherapy of ErbB(+) Solid Tumor Neoplastic Cells
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10112885
Abstract: Chimeric antigen receptor (CAR) immunotherapy includes the genetic modification of immune cells to carry such a receptor and, thus, recognize cancer cell surface antigens. Viral transfection is currently the preferred method, but it carries the… read more here.
Keywords: ivt mrna; delivery platform; car; car immunotherapy ... See more keywords