Oral Delivery of Protein Drugs via Lysine Polymer-Based Nanoparticle Platforms.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300311
Abstract: Oral delivery of proteins has opened a new perspective for the treatment of different diseases. However, advances of oral protein formulation are usually hindered by protein susceptibility and suboptimal absorption in the gastrointestinal tract (GIT).… read more here.
Keywords: lys aapeas; delivery protein; oral delivery; lysine ... See more keywords
Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: From design to therapeutic applications.
Sign Up to like & getrecommendations! Published in 2020 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.9b01754
Abstract: Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential to offer cures for previously untreatable diseases. However, they present an enormous delivery challenge due to… read more here.
Keywords: protein nucleic; delivery; therapeutic delivery; polymersomes therapeutic ... See more keywords
Tannic Acid-Assisted Biomineralization Strategy for Encapsulation and Intracellular Delivery of Protein Drugs.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c15205
Abstract: Protein therapy has been considered to be one of the most direct and safe ways to regulate cell function and treat tumors. However, safe and effective intracellular delivery of protein drugs is still a key… read more here.
Keywords: delivery protein; protein drugs; therapy; intracellular delivery ... See more keywords
Enhanced delivery of protein fused to cell penetrating peptides to mammalian cells
Sign Up to like & getrecommendations! Published in 2019 at "BMB Reports"
DOI: 10.5483/bmbrep.2019.52.5.195
Abstract: Recent progress in cellular reprogramming technology and lineage-specific cell differentiation has provided great opportunities for translational research. Because virus-based gene delivery is not a practical reprogramming protocol, protein-based reprogramming has been receiving attention as a… read more here.
Keywords: cell penetrating; enhanced delivery; cell; delivery ... See more keywords