Quinic Acid-Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with Endothelial Selectins.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201803601
Abstract: Current nanoparticle (NP) drug carriers mostly depend on the enhanced permeability and retention (EPR) effect for selective drug delivery to solid tumors. However, in the absence of a persistent EPR effect, the peritumoral endothelium can… read more here.
Keywords: solid tumors; drug delivery; delivery solid; delivery ... See more keywords
Computational modelling of drug delivery to solid tumour: Understanding the interplay between chemotherapeutics and biological system for optimised delivery systems.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2018.07.013
Abstract: Drug delivery to solid tumour involves multiple physiological, biochemical and biophysical processes taking place across a wide range of length and time scales. The therapeutic efficacy of anticancer drugs is influenced by the complex interplays… read more here.
Keywords: drug delivery; delivery solid; delivery; delivery systems ... See more keywords
Nucleic Acid Delivery by Solid Lipid Nanoparticles Containing Switchable Lipids: Plasmid DNA vs. Messenger RNA
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25245995
Abstract: The development of safe and effective nucleic acid delivery systems remains a challenge, with solid lipid nanoparticle (SLN)-based vectors as one of the most studied systems. In this work, different SLNs were developed, by combination… read more here.
Keywords: acid delivery; delivery solid; delivery; lipid nanoparticles ... See more keywords