Reconsidering the route of drug delivery in refractory multiple sclerosis: Toward a more effective drug accumulation in the central nervous system.
Sign Up to like & getrecommendations! Published in 2023 at "Medicinal research reviews"
DOI: 10.1002/med.21973
Abstract: Multiple sclerosis is a chronic demyelinating disease with different disease phenotypes. The current FDA-approved disease-modifying therapeutics (DMTs) cannot cure the disease, but only alleviate the disease progression. While the majority of patients respond well to… read more here.
Keywords: disease; accumulation; drug delivery; drug ... See more keywords
Delivery strategies: RNA interference in agriculture and human health.
Sign Up to like & getrecommendations! Published in 2017 at "Pest management science"
DOI: 10.1002/ps.4341
Abstract: Crop protection through expression of introduced insecticidal proteins is a well-established technique. Modifications of endogenous gene expression have also been used successfully to produce safe and effective agrochemical products. The existing gene expression regulatory apparatus… read more here.
Keywords: agriculture; strategies rna; delivery; rna interference ... See more keywords
Evaluation of delivery strategies for forest fuels applying a model for Weather-driven Analysis of Forest Fuel Systems (WAFFS)
Sign Up to like & getrecommendations! Published in 2017 at "Applied Energy"
DOI: 10.1016/j.apenergy.2016.12.018
Abstract: Earlier studies have highlighted the importance of quality and quantity in forest fuel supply chains, since these parameters affect product value and handling properties, but both are constantly changing over time. Great monetary losses can… read more here.
Keywords: forest fuel; fuel supply; model weather; fuel ... See more keywords
Gene delivery strategies for therapeutic proteins production in plants: Emerging opportunities and challenges.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2021.107845
Abstract: There are sharply rising demands for pharmaceutical proteins, however shortcomings associated with traditional protein production methods are obvious. Genetic engineering of plant cells has gained importance as a new strategy for protein production. But most… read more here.
Keywords: production; plant; gene delivery; delivery strategies ... See more keywords
An overview of oral insulin delivery strategies (OIDS).
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.03.144
Abstract: Despite tremendous efforts, the world continues its fight against the common chronic disease-diabetes. Diabetes is caused by elevated glucose levels in the blood, which can lead to several complications like glaucoma, cataract, kidney failure, diabetic… read more here.
Keywords: route; delivery strategies; insulin; oral insulin ... See more keywords
Extracellular vesicles: intelligent delivery strategies for therapeutic applications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.09.019
Abstract: &NA; Extracellular vesicles (EV), in particular exosomes, have been the object of intense research, due to their potential to mediate intercellular communication, modulating the phenotype of target cells. The natural properties and functions of EV… read more here.
Keywords: extracellular vesicles; strategies therapeutic; intelligent delivery; delivery ... See more keywords
Drug Delivery Strategies for Platinum-Based Chemotherapy.
Sign Up to like & getrecommendations! Published in 2017 at "ACS nano"
DOI: 10.1021/acsnano.7b04092
Abstract: Few chemotherapeutics have had such an impact on cancer management as cis-diamminedichloridoplatinum(II) (CDDP), also known as cisplatin. The first member of the platinum-based drug family, CDDP's potent toxicity in disrupting DNA replication has led to… read more here.
Keywords: strategies platinum; platinum based; drug delivery; drug ... See more keywords
Emerging mRNA technologies: delivery strategies and biomedical applications.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d1cs00617g
Abstract: The great success achieved by the two highly-effective messenger RNA (mRNA) vaccines during the COVID-19 pandemic highlights the great potential of mRNA technology. Through the evolution of mRNA technology, chemistry has played an important role… read more here.
Keywords: mrna technologies; mrna; biomedical applications; emerging mrna ... See more keywords
Delivery strategies in treatments of leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d1cs00755f
Abstract: Leukemia is a hematological malignancy associated with the uncontrolled proliferation of mutant progenitors, suppressing the production of normal blood cells. Current treatments, including chemotherapy, radiotherapy, and immunotherapy, still lead to unsatisfactory results with a 5… read more here.
Keywords: treatments leukemia; delivery; delivery strategies; strategies treatments ... See more keywords
Biomimetic camouflage delivery strategies for cancer therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Nanoscale"
DOI: 10.1039/d1nr01127h
Abstract: Cancer remains a significant challenge despite the progress in developing different therapeutic approaches. Nanomedicine has been explored as a promising novel cancer therapy. Recently, biomimetic camouflage strategies have been investigated to change the bio-fate of… read more here.
Keywords: strategies cancer; delivery; delivery strategies; cancer ... See more keywords
Engineered biomaterial strategies for controlling growth factors in tissue engineering
Sign Up to like & getrecommendations! Published in 2020 at "Drug Delivery"
DOI: 10.1080/10717544.2020.1831104
Abstract: Abstract Growth factors are multi-functional signaling molecules that coordinate multi-stage process of wound healing. During wound healing, growth factors are transmitted to wound environment in a positive and physiologically related way, therefore, there is a… read more here.
Keywords: biomaterial strategies; engineered biomaterial; growth factors; delivery strategies ... See more keywords