Articles with "delivery system" as a keyword



Electronic Nicotine Delivery System Advertisement Trends After US Federal Policy Changes

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Published in 2025 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2024.59188

Abstract: This qualitative study examines whether changes to US federal policy regarding advertisement of electronic nicotine delivery systems were associated with changes in advertising strategy among brands with marketing authorization. read more here.

Keywords: electronic nicotine; delivery system; federal policy; nicotine delivery ... See more keywords

Port Delivery System With Ranibizumab vs Monitoring in Nonproliferative Diabetic Retinopathy Without Macular Edema

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Published in 2025 at "JAMA Ophthalmology"

DOI: 10.1001/jamaophthalmol.2025.0001

Abstract: Key Points Question Does the Port Delivery System (PDS) with ranibizumab, 100 mg/mL, refilled every 36 weeks, improve Diabetic Retinopathy Severity Scale (DRSS) levels in patients with nonproliferative diabetic retinopathy without center-involved diabetic macular edema… read more here.

Keywords: retinopathy; nonproliferative diabetic; delivery system; retinopathy without ... See more keywords

mRNA Delivery System for Targeting Antigen‐Presenting Cells In Vivo

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Published in 2018 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201800335

Abstract: The encapsulation of mRNA in nanosystems as gene vaccines for immunotherapy purposes has experienced an exponential increase in recent years. Despite the many advantages envisaged within these approaches, their application in clinical treatments is still… read more here.

Keywords: delivery system; presenting cells; mrna delivery; system targeting ... See more keywords

A Bionic Thermosensitive Sustainable Delivery System for Reversing the Progression of Osteoarthritis by Remodeling the Joint Homeostasis

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Published in 2024 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202303792

Abstract: Although the pathogenesis of osteoarthritis (OA) is unclear, inflammatory cytokines are related to its occurrence. However, few studies focused on the therapeutic strategies of regulating joint homeostasis by simultaneously remodeling the anti‐inflammatory and immunomodulatory microenvironments.… read more here.

Keywords: bionic thermosensitive; system; joint homeostasis; thermosensitive sustainable ... See more keywords

Hydrogen Sulfide Delivery System Based on Salting‐Out Effect for Enhancing Synergistic Photothermal and Photodynamic Cancer Therapies

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Published in 2024 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202400803

Abstract: The simultaneous application of photothermal therapy (PTT) and photodynamic therapy (PDT) offers substantial advantages in cancer treatment. However, their synergistic anticancer efficacy is often limited by tumor hypoxia, and thermotolerance induced by high expression of… read more here.

Keywords: cancer; effect; h2s; delivery system ... See more keywords

Fluoroalkane Engineered Magnetic Vectors Unlock the Potential of Gasdermin in Vivo Delivery for Pyroptosis Induced Cancer Therapy

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202500801

Abstract: Pyroptosis, a programmed necrotic cell death mediated by gasdermin, can activate strong immune responses and serve as a potential target for cancer therapy. Nevertheless, the relatively large molecular size and negative surface charge of gasdermin… read more here.

Keywords: delivery system; pyroptosis; gasdermin; delivery ... See more keywords

Intelligent Gene Delivery System Functionalized Metal Implants for Fracture Repair via Remodeling Mitochondrial Homeostasis

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Published in 2025 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202501411

Abstract: Delayed union and nonunion of fractures are primarily attributed to the impaired osteogenic activities of bone marrow mesenchymal stem cells (BMSCs). Gene therapy targeting BMSCs is emerging as a promising strategy to promote fracture healing.… read more here.

Keywords: delivery system; gene delivery; mitochondrial homeostasis; metal implants ... See more keywords

A Versatile Nonviral Delivery System for Multiplex Gene-Editing in the Liver.

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Published in 2020 at "Advanced materials"

DOI: 10.1002/adma.202003537

Abstract: Recent advances in CRISPR present attractive genome-editing toolsets for therapeutic strategies at the genetic level. Here, a liposome-coated mesoporous silica nanoparticle (lipoMSN) is reported as an effective CRISPR delivery system for multiplex gene-editing in the… read more here.

Keywords: gene editing; multiplex gene; delivery system; editing liver ... See more keywords

Biomimetic Targeted Co‐Delivery System Engineered from Genomic Insights for Precision Treatment of Osteosarcoma

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Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202410427

Abstract: The high heterogeneity and severe side effects of chemotherapy are major factors contributing to the failure of osteosarcoma treatment. Herein, a comprehensive genomic analysis is conducted, and identified two prominent characteristics of osteosarcoma: significant cyclin‐dependent… read more here.

Keywords: system; treatment; biomimetic targeted; delivery system ... See more keywords

Biomimetic Nanoplatform for Targeted Rheumatoid Arthritis Therapy: Modulating Macrophage Niches Through Self‐Sustaining Positive Feedback‐Driven Drug Release Mechanisms

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202416265

Abstract: The core strategies in treating rheumatoid arthritis (RA) now focus on ameliorating the inflammatory microenvironment and reversing macrophage phenotypes within the joint cavity. This study introduces a co‐delivery system of integrating nanoenzymes and gene therapeutics… read more here.

Keywords: delivery system; self sustaining; sustaining positive; delivery ... See more keywords

Hydrogels based on copolymers of 2-hydroxyethylmethacrylate and 2-hydroxyethylacrylate as a delivery system for proteins: interactions with lysozyme

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Published in 2017 at "Journal of Applied Polymer Science"

DOI: 10.1002/app.44768

Abstract: Hydrogels have attracted considerable attention due to numerous applications, in particular as contact lenses and carriers for sustained drug delivery. The aim of the present work is to characterize the interactions of copolymer hydrogels consisted… read more here.

Keywords: protein; delivery system; delivery; system proteins ... See more keywords