Polymeric Nanoparticle-Based Vaccine Adjuvants and Delivery Vehicles.
Sign Up to like & getrecommendations! Published in 2020 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2020_226
Abstract: As vaccine formulations have progressed from including live or attenuated strains of pathogenic components for enhanced safety, developing new adjuvants to more effectively generate adaptive immune responses has become necessary. In this context, polymeric nanoparticles… read more here.
Keywords: adjuvants delivery; delivery vehicles; polymeric nanoparticle; delivery ... See more keywords
Characterization of high density lipoprotein from egg yolk and its ability to form nanocomplexes with chitosan as natural delivery vehicles
Sign Up to like & getrecommendations! Published in 2017 at "Food Hydrocolloids"
DOI: 10.1016/j.foodhyd.2017.09.035
Abstract: Abstract In this work, egg yolk high density lipoprotein (HDL) was first extracted and solubilized with a salt-free method. The freshly purified egg yolk HDL was characterized for its physicochemical properties and its delivery potentials… read more here.
Keywords: delivery vehicles; high density; delivery; density lipoprotein ... See more keywords
Microfluidic Preparation of Gelatin Methacryloyl Microgels as Local Drug Delivery Vehicles for Hearing Loss Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c11647
Abstract: Local drug delivery has become an effective method for disease therapy in fine organs including ears, eyes, and noses. However, the multiple anatomical and physiological barriers, unique clearance pathways, and sensitive perceptions characterizing these organs… read more here.
Keywords: hearing loss; delivery; drug delivery; drug ... See more keywords
Length-Controlled Nanofiber Micelleplexes as Efficient Nucleic Acid Delivery Vehicles.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c06695
Abstract: Micelleplexes show great promise as effective polymeric delivery systems for nucleic acids. Although studies have shown that spherical micelleplexes can exhibit superior cellular transfection to polyplexes, to date there has been no report on the… read more here.
Keywords: delivery vehicles; microscopy; nanofiber micelleplexes; nucleic acid ... See more keywords
Controlled drug delivery vehicles for cancer treatment and their performance
Sign Up to like & getrecommendations! Published in 2018 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-017-0004-3
Abstract: Although conventional chemotherapy has been successful to some extent, the main drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse side effects, low therapeutic indices, development of multiple drug resistance, and non-specific targeting. The… read more here.
Keywords: delivery vehicles; drug delivery; delivery; treatment ... See more keywords
Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles.
Sign Up to like & getrecommendations! Published in 2019 at "Signal transduction and targeted therapy"
DOI: 10.1038/s41392-019-0068-3
Abstract: The application of nanomedicines is increasing rapidly with the promise of targeted and efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as evidenced by several preclinical and clinical investigations indicating site-specific drug delivery,… read more here.
Keywords: chronic diseases; delivery vehicles; drug delivery; delivery ... See more keywords
Biomaterials and stem cells as drug/gene delivery vehicles for Parkinson's treatment: an update.
Sign Up to like & getrecommendations! Published in 2021 at "Regenerative medicine"
DOI: 10.2217/rme-2021-0050
Abstract: By introducing biomaterials and stem cells into Parkinson's disease (PD), therapeutic approaches have led to promising results due to facilitating brain targeting and blood-brain barrier permeation of the drugs and genes. Here, after reviewing the… read more here.
Keywords: gene delivery; stem cells; biomaterials stem; delivery vehicles ... See more keywords
Potential of Plant Exosome Vesicles from Grapefruit (Citrus × paradisi) and Tomato (Solanum lycopersicum) Juices as Functional Ingredients and Targeted Drug Delivery Vehicles
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12040943
Abstract: Plant-derived extracellular vesicles (PEVs) have gained attention as promising bioactive nutraceutical molecules; their presence in common fruit juices has increased their significance because human interaction is inevitable. The goal of this study was to evaluate… read more here.
Keywords: functional ingredients; tomato; juices functional; plant ... See more keywords
Lipid Nanoparticles as Delivery Vehicles for Inhaled Therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092179
Abstract: Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery. With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 pandemic, investigations into applying LNPs to deliver inhaled therapeutics directly… read more here.
Keywords: nanoparticles delivery; lipid nanoparticles; delivery; vehicles inhaled ... See more keywords
Towards the Application of Supramolecular Self-Associating Amphiphiles as Next-Generation Delivery Vehicles
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25184126
Abstract: Herein, we present a series of supramolecular self-associating amphiphilic (SSA) salts and establish the potential for these molecular constructs to act as next-generation solution-state molecular delivery vehicles. We characterise the self-association of these SSAs, both… read more here.
Keywords: next generation; supramolecular self; delivery vehicles; self associating ... See more keywords
Mesoporous Silica Nanoparticles as Drug Delivery Vehicles in Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Nanomaterials"
DOI: 10.3390/nano7070189
Abstract: Even though cancer treatment has improved over the recent decades, still more specific and effective treatment concepts are mandatory. Surgical removal is not always possible, metastases are challenging and chemo- and radiotherapy can not only… read more here.
Keywords: delivery vehicles; drug delivery; mesoporous silica; silica nanoparticles ... See more keywords