An intrinsically bioactive hydrogel with on-demand drug release behaviors for diabetic wound healing
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.04.040
Abstract: Prolonged, intense inflammation and excessive oxidative stress hinder diabetic wounds from healing normally, leading to disorders downstream including the postponement of re-epithelialization and extracellular matrix (ECM) formation. Herein, we report a hyaluronic acid (HA) and… read more here.
Keywords: wound healing; drug release; demand drug; oha cmc ... See more keywords
Controlled release of bupivacaine using hybrid thermoresponsive nanoparticles activated via photothermal heating.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2018.03.107
Abstract: Near-infrared (NIR) responsive nanoparticles are of great interest in the biomedical field as antennas for photothermal therapy and also as triggers for on-demand drug delivery. The present work reports the preparation of hollow gold nanoparticles… read more here.
Keywords: photothermal heating; hybrid thermoresponsive; heating; bupivacaine ... See more keywords
Magnetic Induction Heating Enables On-Demand Drug Release via Diels–Alder Polymeric Nanocarriers
Sign Up to like & getrecommendations! Published in 2025 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.5c00321
Abstract: As a stimulus-responsive drug release system, we developed Diels–Alder (DA) induction-activated magnetic nanoparticles (DiMaN). Functionalization of polymer-coated magnetic nanoparticles (mNPs) with drugs via thermoreversible DA coupling enabled release through retro-Diels–Alder (rDA) cleavage upon heating. The… read more here.
Keywords: demand drug; release; drug release; drug ... See more keywords
Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00077
Abstract: Poor aqueous drug solubility represents a major challenge in oral drug delivery. A novel approach to overcome this challenge is drug amorphization inside a tablet, that is, on-demand drug amorphization. The amorphous form is a… read more here.
Keywords: drug; photothermal plasmonic; plasmonic nanoparticles; demand drug ... See more keywords
On-Demand Drug Release from Gold Nanoturf for a Thermo- and Chemotherapeutic Esophageal Stent.
Sign Up to like & getrecommendations! Published in 2018 at "ACS nano"
DOI: 10.1021/acsnano.8b01921
Abstract: Stimuli-responsive delivery systems for cancer therapy have been increasingly used to promote the on-demand therapeutic efficacy of anticancer drugs and, in some cases, simultaneously generate heat in response to a stimulus, resulting in hyperthermia. However,… read more here.
Keywords: esophageal stent; drug; drug release; demand drug ... See more keywords
Monitoring of "on-demand" drug release using dual tumor marker mediated DNA-capped versatile mesoporous silica nanoparticles.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc02752d
Abstract: A versatile drug delivery system with dual specific capacity of controllable release and monitoring of the intracellular release process, which extremely maximize therapeutic efficacy on diseased cells while minimizing drug toxicity to healthy cells, was… read more here.
Keywords: drug; monitoring demand; drug release; demand drug ... See more keywords
Nanoengineered on-demand drug delivery system improves efficacy of pharmacotherapy for epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm3381
Abstract: Electroresponsive and synergistic brain-targeting nanoparticles improve efficacy of pharmacotherapy for epilepsy. read more here.
Keywords: pharmacotherapy epilepsy; nanoengineered demand; drug delivery; demand drug ... See more keywords
Abstract 5751: Ultrasound responsive injectable hydrogels for on-demand drug delivery
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-5751
Abstract: In this work, we developed ultrasound-responsive and injectable hydrogels for local and on-demand release of chemotherapeutics to solid tumors. Injectable hydrogels were prepared by using a zwitterionic monomer, sulfobetaine methacrylate (SBMA), without using any crosslinker.… read more here.
Keywords: demand drug; drug delivery; injectable hydrogels; drug ... See more keywords