Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown
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DOI: 10.1093/brain/awy284
Abstract: See Bechek and Gitler (doi:10.1093/brain/awy294) for a scientific commentary on this article. Mutations in the endosome-associated protein CHMP2B cause frontotemporal dementia (FTD). Clayton et al. report a mechanism for CHMP2B-mediated neuronal dysfunction and a potential… read more here.
Keywords: frontotemporal dementia; chmp2b; causative chmp2b; dementia causative ... See more keywords