Association of Longitudinal β-Amyloid Accumulation Determined by Positron Emission Tomography With Clinical and Cognitive Decline in Adults With Probable Lewy Body Dementia
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.16439
Abstract: Key Points Question What is the trajectory of β-amyloid accumulation over time, and how is it associated with clinical and cognitive decline among patients with probable dementia with Lewy bodies? Findings This cohort study of… read more here.
Keywords: lewy bodies; dementia lewy; accumulation; amyloid accumulation ... See more keywords
Translocator protein in late stage Alzheimer’s disease and Dementia with Lewy bodies brains
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50837
Abstract: Increased translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor (PBR), in glial cells of the brain has been used as a neuroinflammation marker in the early and middle stages of neurodegenerative diseases, such… read more here.
Keywords: lewy bodies; dementia lewy; late stage; alzheimer disease ... See more keywords
Gender difference in the association and presentation of visual hallucinations in dementia with Lewy bodies: a cross‐sectional study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.4706
Abstract: Visual hallucinations (VHs) are among the most striking features of dementia with Lewy bodies (DLB). We investigated gender differences in the association and presentation of VHs in DLB. read more here.
Keywords: lewy bodies; dementia lewy; visual hallucinations; association presentation ... See more keywords
Electroconvulsive therapy improves psychotic symptoms in patients with dementia with Lewy bodies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5832
Abstract: The aim of this study was to examine the efficacy and safety of electroconvulsive therapy (ECT) for psychotic symptoms of dementia with Lewy bodies (DLB), and also to determine its use as an adaptive criterion. read more here.
Keywords: dementia lewy; therapy improves; psychotic symptoms; lewy bodies ... See more keywords
Clinical and imaging correlates of amyloid deposition in dementia with Lewy bodies
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.27403
Abstract: Background: Amyloid deposition is common in dementia with Lewy bodies, but its pathophysiological significance is unclear. read more here.
Keywords: lewy bodies; clinical imaging; dementia lewy; amyloid deposition ... See more keywords
Prodromal Dementia With Lewy Bodies: Clinical Characterization and Predictors of Progression
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DOI: 10.1002/mds.27997
Abstract: The objective of this study was to examine clinical characteristics, cognitive decline, and predictors for time to dementia in prodromal dementia with Lewy bodies with mild cognitive impairment (MCI‐LB) compared with prodromal Alzheimer's disease (MCI‐AD). read more here.
Keywords: lewy bodies; dementia lewy; dementia; prodromal dementia ... See more keywords
Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy
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DOI: 10.1002/mds.28034
Abstract: Multiple system atrophy (MSA) is a rare, untreatable neurodegenerative disorder characterized by accumulation of α‐synuclein in oligodendroglial inclusions. As such, MSA is a synucleinopathy along with Parkinson's disease (PD) and dementia with Lewy bodies. Activation… read more here.
Keywords: lewy bodies; multiple system; system atrophy; dementia lewy ... See more keywords
Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.16-0362
Abstract: Synucleinopathies are a group of neurodegenerative disorders sharing the common feature of misfolding and accumulation of the presynaptic protein α‐synuclein (α‐syn) into insoluble aggregates. Within this diverse group, Dementia with Lewy Bodies (DLB) is characterized… read more here.
Keywords: lewy bodies; medicine; dementia lewy; model ... See more keywords
Cerebrospinal fluid markers analysis in the differential diagnosis of dementia with Lewy bodies and Parkinson’s disease dementia
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-018-0928-9
Abstract: Dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) share a couple of clinical similarities that is often a source of diagnostic pitfalls. We evaluated the discriminatory potential of brain-derived CSF markers [tau, p-tau… read more here.
Keywords: lewy bodies; dementia lewy; dementia; tau tau ... See more keywords
Propagation of alpha-synuclein pathology from the olfactory bulb: possible role in the pathogenesis of dementia with Lewy bodies
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2733-6
Abstract: Olfactory limbic structures, like the amygdala, the entorhinal, and the piriform cortices, are closely involved in cognitive processes. Thus, besides olfactory dysfunctions, it is conceivable that the compromise of these structures can lead to cognitive… read more here.
Keywords: dementia lewy; olfactory bulb; pathology;
Epidemiological information of dementia with Lewy bodies
Sign Up to like & getrecommendations! Published in 2017 at "Neurological Sciences"
DOI: 10.1007/s10072-017-2966-x
Abstract: Dear Editor, I have read the article entitled as BThe Italian dementia with Lewy bodies study group (DLB-SINdem): toward a standardization of clinical procedures and multicenter cohort studies design^ by Bonanni et al. with interest… read more here.
Keywords: lewy bodies; dementia lewy; information; dlb ... See more keywords