Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells
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DOI: 10.18632/oncotarget.16820
Abstract: In glioblastoma several histone demethylase genes (KDM) are overexpressed compared to normal brain tissue and the development of Temozolomide (TMZ) resistance is accompanied by the transient further increased expression of KDM5A and other KDMs following… read more here.
Keywords: glioblastoma cells; jib; histone demethylase; demethylase genes ... See more keywords