GSK-J4: An H3K27 histone demethylase inhibitor, as a potential anti-cancer agent.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of cancer"
DOI: 10.1002/ijc.34559
Abstract: Aberrant epigenetic modifications are emerging as potent drivers of tumor initiation and progression. The deregulation of H3K27me3 marks has shown to play an important role in cancer progression in several cancers. The H3K27me3 mark is… read more here.
Keywords: demethylase inhibitor; cancer; anti cancer; histone demethylase ... See more keywords
Targeted deletion of three CYP51s in Fusarium fujikuroi and their different roles in determining sensitivity to 14α-demethylase inhibitor fungicides.
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7304
Abstract: BACKGROUND Fusarium fujikuroi is the pathogenic agent of rice bakanae disease and has developed serious resistance to prochloraz, a 14α-demethylase inhibitor (DMI). Prochloraz resistance in F. fujikuroi is caused by cooperation between FfCyp51B with Cyp51A… read more here.
Keywords: demethylase inhibitor; sensitivity; three cyp51s; deletion ... See more keywords