Sterol 14-α-demethylase is vital for mitochondrial functions and stress tolerance in Leishmania major
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DOI: 10.1371/journal.ppat.1008810
Abstract: Sterol 14-α-demethylase (C14DM) is a key enzyme in the biosynthesis of sterols and the primary target of azoles. In Leishmania major, genetic or chemical inactivation of C14DM leads to accumulation of 14-methylated sterol intermediates and… read more here.
Keywords: leishmania major; sterol demethylase; demethylase vital; sterol ... See more keywords