Safety and Efficacy of Lotilaner Ophthalmic Solution (0.25%) in Treating Demodex Blepharitis: Pooled Analysis of Two Pivotal Trials
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DOI: 10.1007/s40123-024-01089-5
Abstract: Lotilaner ophthalmic solution (0.25%) is the first United States Food and Drug Administration (US FDA)-approved drug for treating Demodex blepharitis. In pivotal trials, it was found to be well tolerated and demonstrated a significant reduction… read more here.
Keywords: demodex blepharitis; lotilaner ophthalmic; ophthalmic solution; group ... See more keywords
Different Approach to Manage Demodex Blepharitis - Initial and Maintenance Treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Current eye research"
DOI: 10.1080/02713683.2021.1978099
Abstract: PURPOSE/AIM OF THE STUDY To evaluate the improvement of ocular signs and symptoms in patients suffering from Demodex blepharitis using a combined treatment approach: use of eyelid wipes impregnated with 2.5% terpinen-4-ol (T4O) and 0.2%… read more here.
Keywords: maintenance; treatment; demodex blepharitis; period ... See more keywords
Permethrin Cream for the Treatment of Demodex Blepharitis.
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DOI: 10.1097/ico.0000000000002013
Abstract: PURPOSE To evaluate the safety and efficacy of permethrin 5% cream for the treatment of Demodex blepharitis. METHODS Patients with confirmed Demodex blepharitis were prospectively recruited and treated with permethrin 5% cream for 6 months.… read more here.
Keywords: treatment; demodex blepharitis; demodex; blepharitis ... See more keywords
Update on the Management and Treatment of Demodex Blepharitis.
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DOI: 10.1097/ico.0000000000002911
Abstract: ABSTRACT Demodex blepharitis is a common ophthalmologic disease that is often overlooked in the workup of blepharitis. Demodex infestation occurs in both symptomatic and asymptomatic individuals at similar rates; consequently, its role in the development… read more here.
Keywords: management; microscopy; treatment; demodex blepharitis ... See more keywords
Role of Blepharoexfoliation in Demodex Blepharitis: A Randomized Comparative Study
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DOI: 10.1097/ico.0000000000003046
Abstract: Purpose: The purpose of this study was to evaluate the safety and efficacy of blepharoexfoliation in the treatment of Demodex blepharitis. Methods: Patients with microscopically approved Demodex blepharitis were enrolled. Patients in the treatment group… read more here.
Keywords: demodex; demodex blepharitis; blepharoexfoliation; osdi score ... See more keywords
Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis: Results of a Prospective, Randomized, Vehicle-Controlled, Double-Masked, Pivotal Trial (Saturn-1)
Sign Up to like & getrecommendations! Published in 2022 at "Cornea"
DOI: 10.1097/ico.0000000000003097
Abstract: Purpose: The purpose of this study was to evaluate the safety and efficacy of lotilaner ophthalmic solution, 0.25%, compared with vehicle for the treatment of Demodex blepharitis. Methods: In this prospective, randomized, controlled, double-masked, phase… read more here.
Keywords: lotilaner ophthalmic; demodex blepharitis; ophthalmic solution; cure ... See more keywords
Long-Term Outcomes of 6-Week Treatment of Lotilaner Ophthalmic Solution, 0.25%, for Demodex Blepharitis: A Noninterventional Extension Study
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DOI: 10.1097/ico.0000000000003484
Abstract: Supplemental Digital Content is Available in the Text. Purpose: The aim of this study was to evaluate the long-term outcomes of lotilaner ophthalmic solution, 0.25%, in the treatment of Demodex blepharitis. Methods: This observational, extension… read more here.
Keywords: treatment; group; demodex blepharitis; lotilaner ophthalmic ... See more keywords
Ivermectin 1% Combined With Intense Pulsed Light Treatment for Dry Eye Disease Secondary to Demodex Blepharitis.
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DOI: 10.1097/ico.0000000000003774
Abstract: PURPOSE To examine the safety and efficacy of combined treatment with topical ivermectin 1% and intense pulsed light (IPL) for dry eye disease (DED) secondary to demodex blepharitis. METHODS A retrospective review of medical files… read more here.
Keywords: blepharitis; treatment; ivermectin; intense pulsed ... See more keywords
A new digital biomarker of Demodex blepharitis: energy curve of the meibomian edge
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2025.1627327
Abstract: Purpose To develop and validate a novel digital biomarker, the energy curve of the meibomian gland (MG) edge, to assess MG uneven atrophy and aid in diagnosing Demodex blepharitis. Methods A retrospective study enrolled 76… read more here.
Keywords: energy; energy curve; curve; demodex blepharitis ... See more keywords
Metagenomic profiling of ocular surface microbiome changes in Demodex blepharitis patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.922753
Abstract: Purpose To compare the ocular surface and meibum microbial communities of humans with Demodex Blepharitis (DB) and healthy controls. Methods Conjunctival sac and meibum samples from 25 DB patients and 11 healthy controls were analyzed… read more here.
Keywords: group; demodex blepharitis; surface microbiome; ocular surface ... See more keywords
Uneven Index: A Digital Biomarker to Prompt Demodex Blepharitis Based on Deep Learning
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.934821
Abstract: Purpose: To evaluate ocular surface manifestations and morphological changes in meibomian glands (MGs) based on artificial intelligence (AI) analysis in patients with Demodex blepharitis. Methods: In this retrospective study, 115 subjects were enrolled, including 64… read more here.
Keywords: group; uneven index; demodex; demodex blepharitis ... See more keywords