Modeling SNP array ascertainment with Approximate Bayesian Computation for demographic inference
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28539-y
Abstract: Single nucleotide polymorphisms (SNPs) in commercial arrays have often been discovered in a small number of samples from selected populations. This ascertainment skews patterns of nucleotide diversity and affects population genetic inferences. We propose a… read more here.
Keywords: snp array; demographic inference; bayesian computation; approximate bayesian ... See more keywords
fastsimcoal2: demographic inference under complex evolutionary scenarios.
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab468
Abstract: MOTIVATION fastsimcoal2 extends fastsimcoal, a continuous time coalescent-based genetic simulation program, by enabling the estimation of demographic parameters under very complex scenarios from the site frequency spectrum under a maximum-likelihood framework. RESULTS Other improvements include… read more here.
Keywords: demographic inference; evolutionary scenarios; inference complex; complex evolutionary ... See more keywords
Heterogeneity in effective size across the genome: effects on the Inverse Instantaneous Coalescence Rate (IICR) and implications for demographic inference under linked selection.
Sign Up to like & getrecommendations! Published in 2022 at "Genetics"
DOI: 10.1093/genetics/iyac008
Abstract: The relative contribution of selection and neutrality in shaping species genetic diversity is one of the most central and controversial questions in evolutionary theory. Genomic data provide growing evidence that linked selection, i.e. the modification… read more here.
Keywords: demographic inference; coalescence; linked selection; size ... See more keywords