Atypical Pediatric Demyelinating Diseases of the Central Nervous System
Sign Up to like & getrecommendations! Published in 2019 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-019-1015-y
Abstract: Pediatric central nervous system demyelinating diseases include multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and acute disseminated encephalomyelitis (ADEM). As diagnostic criteria become more inclusive, the risk of misdiagnosis of atypical demyelinating diseases of… read more here.
Keywords: sclerosis; diseases central; nervous system; central nervous ... See more keywords
Baló's concentric sclerosis – A rare entity within the spectrum of demyelinating diseases
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2021.117570
Abstract: Baló's concentric sclerosis (BCS) is a rare, inflammatory demyelinating disease of the central nervous system (CNS). Historically, BCS was thought to be uniformly fatal and diagnosis was based on postmortem findings. With advances in modern… read more here.
Keywords: sclerosis; bal concentric; concentric sclerosis; bcs ... See more keywords
QKI-V5 is downregulated in CNS inflammatory demyelinating diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2019.101881
Abstract: BACKGROUND Neuromyelitis-optica (NMO) and multiple-sclerosis (MS) are inflammatory- demyelinating-diseases of the central-nervous-system (CNS). In a previous study, we identified 17 miRNAs that were significantly upregulated in the peripheral blood of patients with NMO, relative to… read more here.
Keywords: inflammatory demyelinating; qki; demyelinating diseases; expression ... See more keywords
Neuropsychological outcomes of pediatric demyelinating diseases: a review
Sign Up to like & getrecommendations! Published in 2018 at "Child Neuropsychology"
DOI: 10.1080/09297049.2017.1339785
Abstract: ABSTRACT Immune-mediated central nervous system (CNS) demyelinating diseases impact various areas of the brain, optic nerves, and/or spinal cord and can result in a wide range of neurologic symptoms including adverse cognitive outcomes. Neuropsychological outcomes… read more here.
Keywords: diseases review; outcomes pediatric; neuropsychological outcomes; demyelinating diseases ... See more keywords
Ferroptosis and central nervous system demyelinating diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurochemistry"
DOI: 10.1111/jnc.15831
Abstract: Ferroptosis is a newly discovered programmed cell death caused by intracellular iron excess and glutathione (GSH) system imbalance, resulting in fatal lipid peroxidation. It is different from necrosis, apoptosis, autophagy and other forms of cell… read more here.
Keywords: system; ferroptosis central; central nervous; system demyelinating ... See more keywords
Efficacy and safety of plasma exchange or immunoadsorption for the treatment of option neuritis in demyelinating diseases: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of ophthalmology"
DOI: 10.1177/11206721211065218
Abstract: BACKGROUND There are no systematic reviews yet that evaluated the effects of PE/IA in patients with optic neuritis (ON) in demyelinating diseases. A meta-analysis of available study is needed to further explore the value of… read more here.
Keywords: demyelinating diseases; ophthalmology; treatment; neuritis demyelinating ... See more keywords
Ultra-high-field 7-T MRI in multiple sclerosis and other demyelinating diseases: from pathology to clinical practice
Sign Up to like & getrecommendations! Published in 2020 at "European Radiology Experimental"
DOI: 10.1186/s41747-020-00186-x
Abstract: Magnetic resonance imaging (MRI) is essential for the early diagnosis of multiple sclerosis (MS), for investigating the disease pathophysiology, and for discriminating MS from other neurological diseases. Ultra-high-field strength (7-T) MRI provides a new tool… read more here.
Keywords: demyelinating diseases; ultra high; pathology; multiple sclerosis ... See more keywords
Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0184927
Abstract: Purpose Optic neuritis is highly correlated with multiple sclerosis and is a major cause of acute visual loss and long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated… read more here.
Keywords: pct; demyelinating diseases; optic neuritis; hypoperfusion ... See more keywords
Differential diagnosis of demyelinating diseases: what's new?
Sign Up to like & getrecommendations! Published in 2022 at "Arquivos de Neuro-Psiquiatria"
DOI: 10.1590/0004-282x-anp-2022-s109
Abstract: ABSTRACT Background: Acquired demyelinating disorders lead to overlapping visual, pyramidal, sensory, autonomic, and cerebellar deficits and may lead to severe disability. Early diagnosis and start of treatment are fundamental towards preventing further attacks and halting… read more here.
Keywords: diagnosis; diseases new; demyelinating disorders; differential diagnosis ... See more keywords
Exosomal Circular RNA as a Biomarker Platform for the Early Diagnosis of Immune-Mediated Demyelinating Disease
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00860
Abstract: Exosomes can pass through the blood-brain barrier and are present in the cerebrospinal fluid (CSF). The components in exosomes, such as DNA, RNA, protein, and lipids, change greatly and are closely related to disease progression.… read more here.
Keywords: mediated demyelinating; hsa circ; demyelinating diseases; immune mediated ... See more keywords
Anti-IL-6 therapies in central nervous system inflammatory demyelinating diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.966766
Abstract: Current treatments for central nervous system (CNS) inflammatory demyelinating diseases (IDDs) include corticosteroids, plasma exchange, intravenous immunoglobulin, and immunosuppressant drugs. However, some patients do not respond well to traditional therapies. In recent years, novel drugs,… read more here.
Keywords: central nervous; anti therapies; nervous system; demyelinating diseases ... See more keywords