Demyelination in hereditary sensory neuropathy type‐1C
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DOI: 10.1002/acn3.51110
Abstract: Sphingolipids are enriched in the nerves. Serine‐palmitoyltransferase (SPT) catalyzes the key step of sphingolipids biosynthesis. Mutations in SPT subunits (SPTLC) lead to the excessive production of neurotoxic deoxysphingolipids (DoxSLs) in patients with Hereditary Sensory Neuropathy… read more here.
Keywords: sensory neuropathy; pathology; hereditary sensory; demyelination hereditary ... See more keywords