Conditional Demyelination and Remyelination in a Transgenic Xenopus laevis.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9072-6_14
Abstract: Multiple sclerosis (MS) is the first cause of acquired disability progression in the young adult. Pathology of MS associates inflammation, demyelination, and neurodegeneration. The development of immunotherapies, by reducing the relapse rate, has profoundly impacted… read more here.
Keywords: demyelination; xenopus laevis; remyelination; conditional demyelination ... See more keywords
Optical Probing of Hippocampal Function in a Mouse Model of Demyelination/Remyelination
Sign Up to like & getrecommendations! Published in 2020 at "Brain"
DOI: 10.1364/brain.2020.bw2c.6
Abstract: Nonlinear microscopy of calcium sensors was used to record hippocampal activity during induced demyelination and remyelination of axons for 100 days. Substantial changes to firing rates were identified during demyelination with partial recovery upon remyelination. read more here.
Keywords: demyelination; remyelination; optical probing; probing hippocampal ... See more keywords
Oligodendroglial primary cilium heterogeneity during development and demyelination/remyelination
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1049468
Abstract: The primary cilium (PC) has emerged as an indispensable cellular antenna essential for signal transduction of important cell signaling pathways. The rapid acquisition of knowledge about PC biology has raised attention to PC as a… read more here.
Keywords: remyelination; development; demyelination remyelination; cilium ... See more keywords
Deciphering the Genetic Crosstalk between Microglia and Oligodendrocyte Precursor Cells during Demyelination and Remyelination Using Transcriptomic Data
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232314868
Abstract: Demyelinating disorders show impaired remyelination due to failure in the differentiation of oligodendrocyte progenitor cells (OPCs) into mature myelin-forming oligodendrocytes, a process driven by microglia–OPC crosstalk. Through conducting a transcriptomic analysis of microarray studies on… read more here.
Keywords: crosstalk microglia; remyelination; oligodendrocyte; analysis ... See more keywords