Denatured corona proteins mediate the intracellular bioactivities of nanoparticles via the unfolded protein response.
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DOI: 10.1016/j.biomaterials.2020.120452
Abstract: Biomolecular corona formed on nanoparticles (NPs) influences the latter's in vivo biological effects. Nanomaterials with different physicochemical properties exert similar adverse effects, such as cytotoxicity, suggesting the existence of ubiquitous signals during various corona formations… read more here.
Keywords: protein; response; unfolded protein; protein response ... See more keywords