Functional dual hydrophilic dendrimer‐modified metal‐organic framework for the selective enrichment of N‐glycopeptides
Sign Up to like & getrecommendations! Published in 2017 at "PROTEOMICS"
DOI: 10.1002/pmic.201700005
Abstract: Analysis of protein glycosylation remains a significant challenge due to the low abundance of glycoproteins or N‐glycopeptides. Here we have synthesized an amino‐functionalized metal‐organic framework (MOF) MIL‐101(Cr)‐NH2 whose surface is grafted with a hydrophilic dendrimer… read more here.
Keywords: dual hydrophilic; dendrimer; hydrophilic dendrimer; metal organic ... See more keywords
Folate-Decorated Polyamidoamine Dendrimer Nanoparticles for Head and Neck Cancer Gene Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9220-1_26
Abstract: Gene delivery systems have been developed on the basis of dendrimers and many other types of nanoparticle carriers, but few have been developed for head and neck squamous cell carcinomas (HNSCC). Herein, we describe the… read more here.
Keywords: decorated polyamidoamine; dendrimer; gene therapy; hnscc ... See more keywords
Synthesis of Cationic Amphiphilic Surface-Block Polyester Dendrimers
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Inorganic and Organometallic Polymers and Materials"
DOI: 10.1007/s10904-017-0651-4
Abstract: AbstractCationic amphiphilic polyester dendrimers possessing varied numbers of choline and alkyl chains on the periphery were synthesized and characterized. A combination of divergent and convergent synthetic routes was used to efficiently prepare the dendrimers. All… read more here.
Keywords: dendrimer; cationic amphiphilic; polyester; synthesis cationic ... See more keywords
Emerging Opportunities in the Biomedical Applications of Dendrimers
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DOI: 10.1007/s10904-017-0768-5
Abstract: The medical field remains challenged with many unmet needs, prompting rigorous research for solutions. Dendrimers are emerging as innovative solutions to many unmet clinical needs. Indeed, commercial dendrimer-enabled gene transfection technologies exist and work is… read more here.
Keywords: applications dendrimers; dendrimer; dendrimers emerging; opportunities biomedical ... See more keywords
Engineering of “critical nanoscale design parameters” (CNDPs) in PAMAM dendrimer nanoparticles for drug delivery applications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-018-4318-z
Abstract: Dendrimers are widely recognized as members of the fourth major architectural class of polymers after linear, cross-linked, and branched architectural types. They have become a desirable polymer category for drug delivery applications based on the… read more here.
Keywords: dendrimer; drug delivery; nanoscale design; critical nanoscale ... See more keywords
Dendrimer–didox nanocomplex for enhanced anticancer activity
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DOI: 10.1007/s11051-020-04802-0
Abstract: Didox (DX; 3,4-dihydroxy benzo-hydroxamic acid), a derivative of hydroxamic acid, is a potent inhibitor of ribonucleotide reductase (RR), the enzyme responsible for deoxyribonucleotide synthesis. While RR inhibitors such as hydroxyurea and others are being used… read more here.
Keywords: didox nanocomplex; dendrimer; didox; dendrimer didox ... See more keywords
Ultrasound-enhanced fluorescence imaging and chemotherapy of multidrug-resistant tumors using multifunctional dendrimer/carbon dot nanohybrids
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DOI: 10.1016/j.bioactmat.2020.09.015
Abstract: Development of innovative nanomedicine enabling enhanced theranostics of multidrug-resistant (MDR) tumors remains to be challenging. Herein, we report the development of a newly designed multifunctional yellow-fluorescent carbon dot (y-CD)/dendrimer nanohybrids as a platform for ultrasound… read more here.
Keywords: carbon dot; fluorescence; dendrimer; fluorescence imaging ... See more keywords
A dispersive magnetic solid phase microextraction based on ionic liquid-coated and cyclodextrin-functionalized magnetic core dendrimer nanocomposites for the determination of pyrethroids in juice samples.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.06.105
Abstract: A novel dispersive magnetic solid phase microextraction method based on ionic liquid-coated and cyclodextrin-functionalized magnetic core dendrimer nanocomposites has been developed for the determination of pyrethroids in juice samples. The different generation magnetic core dendrimer… read more here.
Keywords: magnetic core; core dendrimer; dendrimer; dendrimer nanocomposites ... See more keywords
Influence of peptide dendrimers and sonophoresis on the transdermal delivery of ketoprofen.
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DOI: 10.1016/j.ijpharm.2017.02.002
Abstract: The aim of this study was to determine the individual and combined effects of peptide dendrimers and low frequency ultrasound on the transdermal permeation of ketoprofen. Arginine terminated peptide dendrimers of varying charges (4+, 8+… read more here.
Keywords: dendrimer; permeation; drug; ketoprofen ... See more keywords
Electrostatically assembled dendrimer complex with a high‐affinity protein binder for targeted gene delivery
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.04.015
Abstract: Graphical abstract Figure. No Caption available. Abstract Although a variety of non‐viral gene delivery systems have been developed, they still suffer from low efficiency and specificity. Herein, we present the assembly of a dendrimer complex… read more here.
Keywords: dendrimer; gene delivery; dendrimer complex; targeted gene ... See more keywords
Cellular delivery of doxorubicin mediated by disulfide reduction of a peptide‐dendrimer bioconjugate
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.04.027
Abstract: ABSTRACT In this study, we developed a peptide‐dendrimer‐drug conjugate system for the pH‐triggered direct cytosolic delivery of the cancer chemotherapeutic doxorubicin (DOX) using the pH Low Insertion Peptide (pHLIP). We synthesized a pHLIP‐dendrimer‐DOX conjugate in… read more here.
Keywords: conjugate; dendrimer; delivery; peptide dendrimer ... See more keywords