Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110483
Abstract: The development of the apical dendrite from the leading process of the bipolar pyramidal neuron might be directed by spatially organized extrinsic cues acting on localized intrinsic determinants. The extracellular cues regulating apical dendrite polarization… read more here.
Keywords: development; apical dendrite; cgmp increase; dendrite development ... See more keywords
Aging impairs dendrite morphogenesis of newborn neurons and is rescued by 7, 8‐dihydroxyflavone
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DOI: 10.1111/acel.12553
Abstract: All aging individuals will develop some degree of decline in cognitive capacity as time progresses. The molecular and cellular mechanisms leading to age‐related cognitive decline are still not fully understood. Through our previous research, we… read more here.
Keywords: dihydroxyflavone; newborn neurons; development newborn; aging impairs ... See more keywords
Eltrombopag, a thrombopoietin mimetic, crosses the blood–brain barrier and impairs iron‐dependent hippocampal neuron dendrite development
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13602
Abstract: Essentials Potential neurodevelopmental side effects of thrombopoietin mimetics need to be considered. The effects of eltrombopag (ELT) on neuronal iron status and dendrite development were assessed. ELT crosses the blood–brain barrier and causes iron deficiency… read more here.
Keywords: blood brain; iron; brain barrier; dendrite development ... See more keywords
TIAM-1 differentially regulates dendritic and axonal microtubule organization in patterning neuronal development through its multiple domains
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DOI: 10.1371/journal.pgen.1010454
Abstract: Axon and dendrite development require the cooperation of actin and microtubule cytoskeletons. Microtubules form a well-organized network to direct polarized trafficking and support neuronal processes formation with distinct actin structures. However, it is largely unknown… read more here.
Keywords: development; dendrite development; microtubule; microtubule organization ... See more keywords