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Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2589-7
Abstract: Proper communication among neurons depends on an appropriately formed dendritic arbor, and thus, aberrant changes to the arbor are implicated in many pathologies, ranging from cognitive disorders to neurodegenerative diseases. Due to the importance of…
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Keywords:
dendritic arbor;
brain derived;
derived neurotrophic;
branching ... See more keywords
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Published in 2021 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001399
Abstract: Ischemic stroke is a major cause of death and long-term disability. We demonstrate that middle cerebral artery occlusion (MCAO) in mice leads to a strong decline in dendritic arborization of penumbral neurons. These defects were…
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Keywords:
actin nucleator;
nucleator cobl;
cobl;
poststroke dendritic ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0169792
Abstract: Astroglia play key roles in the development of neurons, ranging from regulating neuron survival to promoting synapse formation, yet basic questions remain about whether astrocytes might be involved in forming the dendritic arbor. Here, we…
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Keywords:
dendritic arbor;
interactions astroglia;
dendritic growth;
dendrite growth ... See more keywords
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Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.845291
Abstract: The APOE gene is diversified by three alleles ε2, ε3, and ε4 encoding corresponding apolipoprotein (apo) E isoforms. Possession of the ε4 allele is signified by increased risks of age-related cognitive decline, Alzheimer’s disease (AD),…
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Keywords:
transcriptomic profile;
arbor;
apoe2 apoe3;
hippocampal neurons ... See more keywords