FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.03.037
Abstract: Mutations in the nuclear localization signal of the RNA binding protein FUS cause both Frontotemporal Dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS). These mutations result in a loss of FUS from the nucleus and the… read more here.
Keywords: drosophila; hyperexcitability; caz; fus ... See more keywords
Dscam1: Is It a Ubiquitous Code for Dendritic Arborization?
Sign Up to like & getrecommendations! Published in 2023 at "eNeuro"
DOI: 10.1523/eneuro.0440-22.2023
Abstract: Down syndrome cell adhesion molecule ( DSCAM ) is lo-cated on human chromosome 21 and triplicated in Down syndrome. DSCAM encodes an Ig superfamily cell surface receptor found in both vertebrates and invertebrates. Alternative splicing… read more here.
Keywords: dscam1 ubiquitous; dendritic arborization; code dendritic; ubiquitous code ... See more keywords
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization
Sign Up to like & getrecommendations! Published in 2022 at "EMBO reports"
DOI: 10.15252/embr.202254911
Abstract: Major depressive disorder (MDD) is a severe mental illness. Decreased brain plasticity and dendritic fields have been consistently found in MDD patients and animal models; however, the underlying molecular mechanisms remain to be clarified. Here,… read more here.
Keywords: like behaviors; cip2a deficiency; dendritic arborization; depression like ... See more keywords
Activation of Transient Receptor Potential Vanilloid 4 Impairs the Dendritic Arborization of Newborn Neurons in the Hippocampal Dentate Gyrus through the AMPK and Akt Signaling Pathways
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2017.00190
Abstract: Neurite growth is an important process for the adult hippocampal neurogenesis which is regulated by a specific range of the intracellular free Ca2+ concentration ([Ca2+]i). Transient receptor potential vanilloid 4 (TRPV4) is a calcium-permeable channel… read more here.
Keywords: arborization newborn; dendritic arborization; newborn neurons; transient receptor ... See more keywords