Synthesis of dendritic bisphosphonates as bone targeting ligands
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DOI: 10.1016/j.tetlet.2018.11.028
Abstract: Abstract A dendritic bisphosphonate carrying three bisphosphonate (BP) units in close proximity was designed as a ligand to conjugate large therapeutic molecules for their bone selective delivery. The Bu3P-catalyzed conjugate addition of nitromethane to vinylidene… read more here.
Keywords: bone targeting; dendritic bisphosphonates; targeting ligands; bisphosphonates bone ... See more keywords