Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma
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DOI: 10.1016/j.ebiom.2017.09.005
Abstract: Cytoplasmic aggregation of fused in sarcoma (FUS) is detected in brain regions affected by amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which compose the disease spectrum, FUS proteinopathy. To understand the pathomechanism of ALS-FTD-associated… read more here.
Keywords: frontotemporal dementia; dendritic homeostasis; fus; homeostasis disruption ... See more keywords