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Published in 2019 at "Biophysical Reviews"
DOI: 10.1007/s12551-019-00508-3
Abstract: Proteases from flaviviruses have gained substantial interest as potential drug targets to combat infectious diseases caused by dengue, West Nile, Zika and related viruses. Despite nearly two decades of drug discovery campaigns, promising lead compounds…
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Keywords:
drug targets;
proteases dengue;
drug;
west nile ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14112535
Abstract: Dengue, West Nile and Zika viruses are vector-borne flaviviruses responsible for numerous disease outbreaks in both Hemispheres. Despite relatively low mortality, infection may lead to potentially severe situations such as (depending on the virus): hypovolemic…
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Keywords:
nile zika;
dengue west;
discovery preclinical;
west nile ... See more keywords