Temperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-01097-5
Abstract: Dengue and Zika are two of the most important human viral pathogens worldwide. In both cases, the envelope glycoprotein E is the main target of the antibody response. Recently, new complex quaternary epitopes were identified… read more here.
Keywords: zika viruses; dengue zika; viruses mammalian; mammalian cells ... See more keywords
Dengue, Zika and chikungunya during pregnancy: pre- and post-travel advice and clinical management
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DOI: 10.1093/jtm/taz077
Abstract: Abstract Rationale for review Young adults of childbearing age and pregnant women are travelling more frequently to tropical areas, exposing them to specific arboviral infections such as dengue, zika and chikungunya viruses, which may impact… read more here.
Keywords: pregnancy; zika chikungunya; dengue zika; post travel ... See more keywords
A Novel Series of Indole Alkaloid Derivatives Inhibit Dengue and Zika Virus Infection by Interference with the Viral Replication Complex
Sign Up to like & getrecommendations! Published in 2021 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02349-20
Abstract: Here, we identified a novel class of compounds which demonstrated good antiviral activity against dengue and Zika virus infection. These derivatives constitute intermediates in the synthesis of indole (ervatamine-silicine) alkaloids and share a tetracyclic structure,… read more here.
Keywords: virus infection; dengue zika; replication; infection ... See more keywords
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil
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DOI: 10.1186/s12879-020-05611-5
Abstract: Background The State of Ceará, in Northeastern Brazil, suffers from a triple burden of arboviruses (dengue, Zika and chikungunya). We measured the seroprevalence of chikungunya, dengue and Zika and its associated factors in the population… read more here.
Keywords: seroprevalence; infection; dengue zika; study ... See more keywords
Climatic and socio-economic factors supporting the co-circulation of dengue, Zika and chikungunya in three different ecosystems in Colombia
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0009259
Abstract: Dengue, Zika and chikungunya are diseases of global health significance caused by arboviruses and transmitted by the mosquito Aedes aegypti, which is of worldwide circulation. The arrival of the Zika and chikungunya viruses to South… read more here.
Keywords: zika chikungunya; dengue zika; dengue; socio economic ... See more keywords
Dengue, Zika, and Chikungunya viral circulation and hospitalization rates in Brazil from 2014 to 2019: An ecological study
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010602
Abstract: Background In addition to their direct pathogenic effects, arthropod-borne (arboviruses) have been hypothesized to indirectly contribute to hospitalizations and death through decompensation of pre-existing comorbidities. Using nationwide data routinely collected from 1 January 2014 to… read more here.
Keywords: hospitalization rates; chikungunya viral; 2014 2019; hospitalization ... See more keywords
Wolbachia wAlbB inhibit dengue and Zika infection in the mosquito Aedes aegypti with an Australian background
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010786
Abstract: Biological control of mosquito vectors using the insect-specific bacteria Wolbachia is an emerging strategy for the management of human arboviral diseases. We recently described the development of a strain of Ae. aegypti infected with the… read more here.
Keywords: infection; strain; walbb2; dengue zika ... See more keywords
Overlap between dengue, Zika and chikungunya hotspots in the city of Rio de Janeiro
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DOI: 10.1371/journal.pone.0273980
Abstract: Background Arboviruses represent a threat to global public health. In the Americas, the dengue fever is endemic. This situation worsens with the introduction of emerging, Zika fever and chikungunya fever, causing epidemics in several countries… read more here.
Keywords: city rio; dengue; fever; rio janeiro ... See more keywords
Variability in Susceptibility to Type I Interferon Response and Subgenomic RNA Accumulation Between Clinical Isolates of Dengue and Zika Virus From Oaxaca Mexico Correlate With Replication Efficiency in Human Cells and Disease Severity
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DOI: 10.3389/fcimb.2022.890750
Abstract: Dengue and Zika viruses cocirculate annually in endemic areas of Mexico, causing outbreaks of different magnitude and severity every year, suggesting a continuous selection of Flavivirus variants with variable phenotypes of transmissibility and virulence. To… read more here.
Keywords: dengue zika; susceptibility; subgenomic rna; type interferon ... See more keywords
Host immune response against DENV and ZIKV infections
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DOI: 10.3389/fcimb.2022.975222
Abstract: Dengue is a major public health concern, affecting almost 400 million people worldwide, with about 70% of the global burden of disease in Asia. Despite revised clinical classifications of dengue infections by the World Health… read more here.
Keywords: dengue infections; dengue; dengue zika; response ... See more keywords
The Dual Role of the Antibody Response Against the Flavivirus Non-structural Protein 1 (NS1) in Protection and Immuno-Pathogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01651
Abstract: Dengue and Zika viruses are closely related mosquito-borne flaviviruses responsible for major public health problems in tropical and sub-tropical countries. The genomes of both, dengue and zika viruses encodes 10 genes that are translated into… read more here.
Keywords: protein; structural protein; protein ns1; dengue zika ... See more keywords