Articles with "dense granule" as a keyword



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A Newly Discovered Dense Granule Protein 3 in Neospora caninum.

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Published in 2021 at "Acta parasitologica"

DOI: 10.1007/s11686-021-00402-7

Abstract: INTRODUCTION Neospora caninum, an obligate intracellular parasite of the phylum Apicomplexa, typically causes an illness known as neosporosis. Dense granule proteins (GRAs) are secreted by apicomplexan and constitute the parasitophorous vacuoles (PVs) structure where tachyzoites… read more here.

Keywords: protein; ncgra3 protein; dense granule; neospora caninum ... See more keywords
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GRA12, a novel dense granule protein from Neospora caninum.

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Published in 2020 at "Parasitology international"

DOI: 10.1016/j.parint.2020.102268

Abstract: Neospora caninum, an obligate intracellular parasite of the phylum Apicomplexa, is a major cause of abortion in cattle. After invasion, tachyzoites can reside in the parasitophorous vacuole (PV) and ingest nutrition through the intravacuolar network… read more here.

Keywords: protein; dense granule; ncgra12 protein; neospora caninum ... See more keywords
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Gelsolin Modulates Platelet Dense Granule Secretion and Hemostasis via the Actin Cytoskeleton

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Published in 2022 at "Thrombosis and Haemostasis"

DOI: 10.1055/s-0042-1758800

Abstract: BACKGROUND AND OBJECTIVE  The mechanisms underlying platelet granule release are not fully understood. The actin cytoskeleton serves as the platelet's structural framework that is remodeled upon platelet activation. Gelsolin is a calcium-dependent protein that severs… read more here.

Keywords: gsn platelets; dense granule; actin cytoskeleton; granule secretion ... See more keywords
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An Optimized Assay for Assessing Platelet Dense Granule Secretion Using Diluted Whole Blood

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Published in 2019 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqz112.044

Abstract: Assessment of dense granule secretion following agonist stimulation is an integral part of platelet function testing and can be performed in the clinical laboratory using lumi-aggregometry. A significant limitation of traditional lumi-aggregometry is the relatively… read more here.

Keywords: diluted whole; dense granule; whole blood; blood ... See more keywords
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Dense granule biogenesis, secretion, and function in Toxoplasma gondii

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Published in 2022 at "Journal of Eukaryotic Microbiology"

DOI: 10.1111/jeu.12904

Abstract: Toxoplasma gondii is an obligate intracellular parasite and the causative agent of Toxoplasmosis. A key to understanding and treating the disease lies with determining how the parasite can survive and replicate within cells of its… read more here.

Keywords: dense granule; granule biogenesis; dense; secretion ... See more keywords
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Functional Characterization of 15 Novel Dense Granule Proteins in Toxoplasma gondii Using the CRISPR-Cas9 System

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Published in 2022 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.03078-22

Abstract: Dense granule proteins (GRAs) play important roles in Toxoplasma gondii pathogenicity. However, the functions of many putative GRAs have not been elucidated. ABSTRACT The analysis of the subcellular localization and function of dense granule proteins… read more here.

Keywords: granule proteins; dense granule; gra genes; gondii ... See more keywords
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Molecular detection and dense granule antigen 6 genotyping of feline Toxoplasma gondii in Phayao, Thailand

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Published in 2022 at "Veterinary World"

DOI: 10.14202/vetworld.2022.2309-2314

Abstract: Background and Aim: Globally, toxoplasmosis is an important zoonotic parasite infection of many warm-blooded animals (including humans). Toxoplasma gondii oocysts are widespread, and their contamination can be primarily attributed to the members of the Felidae… read more here.

Keywords: dense granule; thailand; granule antigen; gondii ... See more keywords
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Antigenic properties of dense granule antigen 12 protein using bioinformatics tools in order to improve vaccine design against Toxoplasma gondii

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Published in 2020 at "Clinical and Experimental Vaccine Research"

DOI: 10.7774/cevr.2020.9.2.81

Abstract: Purpose Toxoplasma gondii is an opportunistic parasite infecting all warm-blooded animals including humans. The dense granule antigens (GRAs) play an important role in parasite survival and virulence and in forming the parasitophorous vacuole. Identification of… read more here.

Keywords: protein; dense granule; protein using; vaccine ... See more keywords