Association of Plasma High-Density Lipoprotein Cholesterol Level With Risk of Fractures in Healthy Older Adults.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.5124
Abstract: Importance Increased levels of high-density lipoprotein cholesterol (HDL-C) have been associated with osteoporosis. Preclinical studies have reported that HDL-C reduces bone mineral density by reducing osteoblast number and function. However, the clinical significance of these… read more here.
Keywords: older adults; high density; risk; density lipoprotein ... See more keywords
Cost-effectiveness of Financial Incentives for Patients and Physicians to Manage Low-Density Lipoprotein Cholesterol Levels
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2018.2008
Abstract: Key Points Question Are reductions in cardiovascular disease risk produced by financial incentives placed on patients, physicians, or both to control low-density lipoprotein cholesterol levels worth the costs needed to achieve these health benefits? Findings… read more here.
Keywords: patients physicians; low density; density lipoprotein; lipoprotein cholesterol ... See more keywords
High‐density lipoprotein‐like particle formation of Synuclein variants
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12543
Abstract: α‐Synuclein (α‐Syn) is an intrinsically disordered protein in solution whose fibrillar aggregates are the hallmark of Parkinson's disease (PD). Although the specific function of α‐Syn is still unclear, its high structural plasticity is key for… read more here.
Keywords: synuclein; high density; syn; density lipoprotein ... See more keywords
Tumor‐Activatable Nanoparticles Target Low‐Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201614
Abstract: The binding of plasma proteins to nanomedicines is widely considered detrimental to their delivery to tumors. Here, the design of OxPt/SN38 nanoparticle containing a hydrophilic oxaliplatin (OxPt) prodrug in a coordination polymer core and a… read more here.
Keywords: low density; density lipoprotein; receptor; tumor ... See more keywords
Small Dense Low‐Density Lipoprotein Cholesterol and Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26598
Abstract: For decades, it has been suggested that small dense low‐density lipoprotein (sdLDL) may be particularly atherogenic. High levels of sdLDL are associated with an increased risk of ischemic heart disease; however, the association of sdLDL… read more here.
Keywords: small dense; dense low; low density; density lipoprotein ... See more keywords
The platelet to high density lipoprotein ‐cholesterol ratio is a valid biomarker of nascent metabolic syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3403
Abstract: The metabolic syndrome (MetS) is a major global problem, and inflammation and insulin resistance appear to be key underpinnings in this cardio‐metabolic cluster. MetS predisposes to an increased risk of diabetes and atherosclerotic cardiovascular disease… read more here.
Keywords: high density; density lipoprotein; cholesterol; metabolic syndrome ... See more keywords
Impact of different training modalities on high‐density lipoprotein function in HFpEF patients: a substudy of the OptimEx trial
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14032
Abstract: In heart failure with preserved ejection fraction (HFpEF), the reduction of nitric oxide (NO)‐bioavailability and consequently endothelial dysfunction leads to LV stiffness and diastolic dysfunction of the heart. Besides shear stress, high‐density lipoprotein (HDL) stimulates… read more here.
Keywords: high density; density lipoprotein; heart; hfpef patients ... See more keywords
Proteomic diversity of high‐density lipoprotein explains its association with clinical outcome in patients with heart failure
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1101
Abstract: Previously, low high‐density lipoprotein (HDL) cholesterol was found to be one of the strongest predictors of mortality and/or heart failure (HF) hospitalisation in patients with HF. We therefore performed in‐depth investigation of the multifunctional HDL… read more here.
Keywords: heart; high density; density lipoprotein; heart failure ... See more keywords
Higher genetically predicted low-density lipoprotein levels increase the renal cancer risk independent of triglycerides and high-density lipoprotein levels: a Mendelian randomization study.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of cancer"
DOI: 10.1002/ijc.34032
Abstract: The causation between lipids and renal cancer remains inconclusive. Our purpose is to explore the causal relationships between the three primary lipid metabolism-related substances, namely triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) with… read more here.
Keywords: lipoprotein levels; density lipoprotein; renal cancer; cancer ... See more keywords
NOS1‐derived nitric oxide facilitates macrophage uptake of low‐density lipoprotein
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28439
Abstract: Foam cell formation is a hallmark event during atherosclerosis. The current paradigm is that lipid uptake by a scavenger receptor in macrophages initiates necrosis core formation that characterizes atherosclerosis. We report that NOS1‐derived nitric oxide… read more here.
Keywords: derived nitric; density lipoprotein; nos1 derived; low density ... See more keywords
Comparison of three equations for estimating low‐density lipoprotein‐cholesterol in the rural northeastern region of Thailand
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23429
Abstract: Cardiovascular disease is the most common cause of death worldwide, and the detection of LDL‐C contributes to reducing risks. However, the LDL‐C is rarely evaluated according to the gold standard method because it is costly… read more here.
Keywords: estimating low; comparison three; density lipoprotein; low density ... See more keywords