Epiprofin Regulates Enamel Formation and Tooth Morphogenesis by Controlling Epithelial‐Mesenchymal Interactions During Tooth Development
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3024
Abstract: The synchronization of cell proliferation and cytodifferentiation between dental epithelial and mesenchymal cells is required for the morphogenesis of teeth with the correct functional shapes and optimum sizes. Epiprofin (Epfn), a transcription factor belonging to… read more here.
Keywords: morphogenesis; epithelial mesenchymal; tooth development; dental epithelial ... See more keywords
Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep45181
Abstract: Tooth development is initiated by epithelial-mesenchymal interactions via basement membrane (BM) and growth factors. In the present study, we found that nephronectin (Npnt), a component of the BM, is highly expressed in the developing tooth.… read more here.
Keywords: egf like; epithelial stem; proliferation; like repeat ... See more keywords
Tubular dentin formation by TGF-β/BMP signaling in dental epithelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14170
Abstract: OBJECTIVES This study aimed to identify formation of tubular dentin induced by Transforming growth factor-β (TGF-β) and bone morphogenic protein (BMP) signaling pathway in dental epithelial cells. METHODS We collected conditioned medium (CM) of rTGF-β1/rBMP-2… read more here.
Keywords: dental epithelial; tubular dentin; formation; epithelial cells ... See more keywords
Spontaneous calcium responses of SF2 rat dental epithelial cells stably expressing the calcium sensor G-GECO.
Sign Up to like & getrecommendations! Published in 2021 at "Biomedical research"
DOI: 10.2220/biomedres.42.193
Abstract: Genetically-encoded calcium indicators such as G-GECO are useful for studying Ca2+ responses during long-term processes. In this study, we employed a lentiviral vector and established a rat dental epithelial cell line that stably expressed G-GECO… read more here.
Keywords: responses sf2; dental epithelial; calcium; ca2 responses ... See more keywords
Dental Epithelial Stem Cells Express the Developmental Regulator Meis1
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00249
Abstract: MEIS1 is a key developmental regulator of several organs and participates in stem cell maintenance in different niches. However, despite the murine continuously growing incisor being a well described model for the study of adult… read more here.
Keywords: epithelial stem; developmental regulator; dental epithelial; meis1 ... See more keywords
New insight into dental epithelial stem cells: Identification, regulation, and function in tooth homeostasis and repair
Sign Up to like & getrecommendations! Published in 2020 at "World Journal of Stem Cells"
DOI: 10.4252/wjsc.v12.i11.1327
Abstract: Tooth enamel, a highly mineralized tissue covering the outermost area of teeth, is always damaged by dental caries or trauma. Tooth enamel rarely repairs or renews itself, due to the loss of ameloblasts and dental… read more here.
Keywords: epithelial stem; dental epithelial; homeostasis repair; stem ... See more keywords