Progesterone receptor expression in cajal‐retzius cells of the developing rat dentate gyrus: Potential role in hippocampus‐dependent memory
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24485
Abstract: The development of medial temporal lobe circuits is critical for subsequent learning and memory functions later in life. The present study reports the expression of progesterone receptor (PR), a powerful transcription factor of the nuclear… read more here.
Keywords: progesterone receptor; cajal retzius; retzius cells; dentate gyrus ... See more keywords
Neurosteroid dehydroepiandrosterone enhances activity and trafficking of astrocytic GLT‐1 via σ1 receptor‐mediated PKC activation in the hippocampal dentate gyrus of rats
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23175
Abstract: Neurosteroid dehydroepiandrosterone (DHEA) has been reported to exert a potent neuroprotective effect against glutamate‐induced excitotoxicity. However, the underlying mechanism remains to be elucidated. One of the possible mechanisms may be an involvement of astrocytic glutamate… read more here.
Keywords: glt; dentate gyrus; activity; neurosteroid dehydroepiandrosterone ... See more keywords
Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP/PS1 mice
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24137
Abstract: Alzheimer pathology is accompanied by astrogliosis. Reactive astrocytes surrounding amyloid plaques may directly affect neuronal communication, and one of the mechanisms by which astrocytes impact neuronal function is by affecting K+ homeostasis. Here we studied,… read more here.
Keywords: function; kir4 protein; expression; dentate gyrus ... See more keywords
Molecular mechanisms within the dentate gyrus and the perirhinal cortex interact during discrimination of similar nonspatial memories
Sign Up to like & getrecommendations! Published in 2020 at "Hippocampus"
DOI: 10.1002/hipo.23269
Abstract: Differentiating between similar memories is a crucial cognitive function that enables correct episodic memory formation. The ability to separate the components of memories into distinct representations is thought to rely on a computational process known… read more here.
Keywords: molecular mechanisms; dentate gyrus; memory; pattern separation ... See more keywords
Interneuron diversity in the rat dentate gyrus: An unbiased in vitro classification
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23408
Abstract: Information processing in cortical circuits, including the hippocampus, relies on the dynamic control of neuronal activity by GABAergic interneurons (INs). INs form a heterogenous population with defined types displaying distinct morphological, molecular, and physiological characteristics.… read more here.
Keywords: classification; interneuron diversity; dentate; dentate gyrus ... See more keywords
Hippocampal dentate gyrus integrity revealed with ultrahigh resolution diffusion imaging predicts memory performance in older adults
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23456
Abstract: Medial temporal lobe (MTL) atrophy is a core feature of age‐related cognitive decline and Alzheimer's disease (AD). While regional volumes and thickness are often used as a proxy for neurodegeneration, they lack the sensitivity to… read more here.
Keywords: ultrahigh resolution; older adults; resolution diffusion; resolution ... See more keywords
The fibro‐ and cyto‐architecture demarcating the border between the dentate gyrus and CA3 in sheep (Ovis aries) and domestic pig (Sus scrofa domesticus)
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23457
Abstract: The hippocampal formation is essential for spatial navigation and episodic memory. The anatomical structure is largely similar across mammalian species, apart from the deep polymorphic layer of the dentate gyrus and the adjacent part of… read more here.
Keywords: layer; border; gyrus ca3; dentate ... See more keywords
Learning‐related changes in cellular activity within mouse dentate gyrus during trace eyeblink conditioning
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23468
Abstract: Because the dentate gyrus serves as the first site for information processing in the hippocampal trisynaptic circuit, it an important structure for the formation of associative memories. Previous findings in rabbit had recorded populations of… read more here.
Keywords: trace eyeblink; trace; dentate gyrus; eyeblink conditioning ... See more keywords
Perturbed expression pattern of the immediate early gene Arc in the dentate gyrus of GluA1 C‐terminal palmitoylation‐deficient mice
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12044
Abstract: AMPA receptors predominantly mediate fast excitatory synaptic transmission in the mammalian brain. Post‐translational protein S‐palmitoylation of AMPA receptor GluA subunits at their C‐termini reversibly controls the receptors trafficking to and from excitatory glutamatergic synapses. Excitatory… read more here.
Keywords: palmitoylation; dentate gyrus; immediate early; expression ... See more keywords
Increased gyrification and aberrant adult neurogenesis of the dentate gyrus in adult rats
Sign Up to like & getrecommendations! Published in 2017 at "Brain Structure and Function"
DOI: 10.1007/s00429-017-1457-4
Abstract: A remarkable example of maladaptive plasticity is the development of epilepsy after a brain insult or injury to a normal animal or human. A structure that is considered central to the development of this type… read more here.
Keywords: dentate gyrus; brain; adult; adult rats ... See more keywords
Uhrf2 deletion impairs the formation of hippocampus-dependent memory by changing the structure of the dentate gyrus
Sign Up to like & getrecommendations! Published in 2017 at "Brain Structure and Function"
DOI: 10.1007/s00429-017-1512-1
Abstract: Ubiquitin-like with PHD and ring finger domains 2 (Uhrf2) is distributed in many brain regions, including the cortex and hippocampus. Decreased Uhrf2 expression is involved in neurodegenerative disease. A recent study showed Uhrf2 deletion impaired… read more here.
Keywords: dentate gyrus; hippocampus dependent; uhrf2 deletion; memory ... See more keywords