Progesterone receptor expression in cajal‐retzius cells of the developing rat dentate gyrus: Potential role in hippocampus‐dependent memory
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24485
Abstract: The development of medial temporal lobe circuits is critical for subsequent learning and memory functions later in life. The present study reports the expression of progesterone receptor (PR), a powerful transcription factor of the nuclear… read more here.
Keywords: progesterone receptor; cajal retzius; retzius cells; dentate gyrus ... See more keywords
Neurosteroid dehydroepiandrosterone enhances activity and trafficking of astrocytic GLT‐1 via σ1 receptor‐mediated PKC activation in the hippocampal dentate gyrus of rats
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23175
Abstract: Neurosteroid dehydroepiandrosterone (DHEA) has been reported to exert a potent neuroprotective effect against glutamate‐induced excitotoxicity. However, the underlying mechanism remains to be elucidated. One of the possible mechanisms may be an involvement of astrocytic glutamate… read more here.
Keywords: glt; dentate gyrus; activity; neurosteroid dehydroepiandrosterone ... See more keywords
Amyloid‐β plaques affect astrocyte Kir4.1 protein expression but not function in the dentate gyrus of APP/PS1 mice
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24137
Abstract: Alzheimer pathology is accompanied by astrogliosis. Reactive astrocytes surrounding amyloid plaques may directly affect neuronal communication, and one of the mechanisms by which astrocytes impact neuronal function is by affecting K+ homeostasis. Here we studied,… read more here.
Keywords: function; kir4 protein; expression; dentate gyrus ... See more keywords
Molecular mechanisms within the dentate gyrus and the perirhinal cortex interact during discrimination of similar nonspatial memories
Sign Up to like & getrecommendations! Published in 2020 at "Hippocampus"
DOI: 10.1002/hipo.23269
Abstract: Differentiating between similar memories is a crucial cognitive function that enables correct episodic memory formation. The ability to separate the components of memories into distinct representations is thought to rely on a computational process known… read more here.
Keywords: molecular mechanisms; dentate gyrus; memory; pattern separation ... See more keywords
Interneuron diversity in the rat dentate gyrus: An unbiased in vitro classification
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23408
Abstract: Information processing in cortical circuits, including the hippocampus, relies on the dynamic control of neuronal activity by GABAergic interneurons (INs). INs form a heterogenous population with defined types displaying distinct morphological, molecular, and physiological characteristics.… read more here.
Keywords: classification; interneuron diversity; dentate; dentate gyrus ... See more keywords
Hippocampal dentate gyrus integrity revealed with ultrahigh resolution diffusion imaging predicts memory performance in older adults
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23456
Abstract: Medial temporal lobe (MTL) atrophy is a core feature of age‐related cognitive decline and Alzheimer's disease (AD). While regional volumes and thickness are often used as a proxy for neurodegeneration, they lack the sensitivity to… read more here.
Keywords: ultrahigh resolution; older adults; resolution diffusion; resolution ... See more keywords
The fibro‐ and cyto‐architecture demarcating the border between the dentate gyrus and CA3 in sheep (Ovis aries) and domestic pig (Sus scrofa domesticus)
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23457
Abstract: The hippocampal formation is essential for spatial navigation and episodic memory. The anatomical structure is largely similar across mammalian species, apart from the deep polymorphic layer of the dentate gyrus and the adjacent part of… read more here.
Keywords: layer; border; gyrus ca3; dentate ... See more keywords
Learning‐related changes in cellular activity within mouse dentate gyrus during trace eyeblink conditioning
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23468
Abstract: Because the dentate gyrus serves as the first site for information processing in the hippocampal trisynaptic circuit, it an important structure for the formation of associative memories. Previous findings in rabbit had recorded populations of… read more here.
Keywords: trace eyeblink; trace; dentate gyrus; eyeblink conditioning ... See more keywords
AMPA and NMDA receptors in dentate gyrus mediate memory for sucrose in two port discrimination task
Sign Up to like & getrecommendations! Published in 2024 at "Hippocampus"
DOI: 10.1002/hipo.23609
Abstract: Although the phenomenon of memory formation and recall associated with the use of psychotropic drugs has been extensively studied, mechanisms underlying memories for natural reward have not been clarified. Herein, we test the hypothesis that… read more here.
Keywords: dentate gyrus; discrimination; receptors dentate; two port ... See more keywords
The Suprapyramidal and Infrapyramidal Blades of the Dentate Gyrus Exhibit Different GluN Subunit Content and Dissimilar Frequency‐Dependent Synaptic Plasticity In Vivo
Sign Up to like & getrecommendations! Published in 2025 at "Hippocampus"
DOI: 10.1002/hipo.70002
Abstract: The entorhinal cortex sends afferent information to the hippocampus by means of the perforant path (PP). The PP input to the dentate gyrus (DG) terminates in the suprapyramidal (sDG) and infrapyramidal (iDG) blades. Different electrophysiological… read more here.
Keywords: dentate gyrus; plasticity; stimulation; frequency dependent ... See more keywords
Differential Astrocyte‐Supplied NMDAR Co‐Agonist for CA1 Versus Dentate Gyrus Long‐Term Potentiation
Sign Up to like & getrecommendations! Published in 2025 at "Hippocampus"
DOI: 10.1002/hipo.70029
Abstract: In the hippocampus, there is a region and synapse-specific N-methyl-D-aspartate receptor (NMDAR) co-agonist preference for induction of long-term potentiation (LTP). Schaffer collateral (SC)-CA1 synapses, enriched in GluN2A-containing NMDARs, favor D-serine, while medial perforant path (MPP)… read more here.
Keywords: dentate gyrus; nmdar agonist; ca1; long term ... See more keywords