Coordinated expression of p300 and HDAC3 upregulates histone acetylation during dentinogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29470
Abstract: Cellular differentiation is caused by highly controlled modifications in the gene expression but rarely involves a change in the DNA sequence itself. Histone acetylation is a major epigenetic factor that adds an acetyl group to… read more here.
Keywords: dentinogenesis; histone acetylation; acetylation; odontoblast differentiation ... See more keywords
Dentinogenesis and Tooth-Alveolar Bone Complex Defects in BMP9/GDF2 Knockout Mice
Sign Up to like & getrecommendations! Published in 2019 at "Stem Cells and Development"
DOI: 10.1089/scd.2018.0230
Abstract: Tooth development is regulated by sequential and reciprocal epithelium-mesenchymal interactions and their related molecular signaling pathways, such as bone morphogenetic proteins (BMPs). Among the 14 types of BMPs, BMP9 (also known as growth differentiation factor… read more here.
Keywords: bone; tooth development; mice; dentinogenesis ... See more keywords
Conditional Knockout of Raptor/mTORC1 Results in Dentin Malformation
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00250
Abstract: mTORC1 signaling plays an important role in extracellular and intracellular signals, including growth factors, nutrients, energy metabolism, and stress. However, the functional role of mTORC1 in dentinogenesis is unknown. To study the role of Raptor/mTORC1… read more here.
Keywords: raptor mtorc1; rap osx; mtorc1; role ... See more keywords