DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target
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DOI: 10.1371/journal.ppat.1006257
Abstract: Dengue is the most common mosquito-borne viral disease in humans. Changes of lipid-related metabolites in endoplasmic reticulum of dengue virus (DENV) infected cells have been associated with replicative complexes formation. Previously, we reported that DENV… read more here.
Keywords: denv infected; hmgcr; activity; replicative complexes ... See more keywords