Effect of high doses of vitamin D supplementation on dengue virus replication, Toll-like receptor expression, and cytokine profiles on dendritic cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03658-w
Abstract: Dengue, caused by dengue virus (DENV) infection, is a public health problem worldwide. Although DENV pathogenesis has not yet been fully elucidated, the inflammatory response is a hallmark feature in severe DENV infection. Although vitamin… read more here.
Keywords: supplementation; response; infection; denv infection ... See more keywords
miR‐21 promotes dengue virus serotype 2 replication in HepG2 cells
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2017.03.020
Abstract: Abstract Infection with the mosquito transmitted dengue virus (DENV) remains a significant worldwide public health problem. While the majority of infections are asymptomatic, infection can result in a range of symptoms. MicroRNAs (miRNAs) are small… read more here.
Keywords: denv infection; replication; infection; hepg2 cells ... See more keywords
Iminosugars counteract the downregulation of the interferon γ receptor by dengue virus
Sign Up to like & getrecommendations! Published in 2019 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2019.104551
Abstract: The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum α-glucosidase enzymes. Iminosugar treatment of dengue… read more here.
Keywords: receptor; denv infection; treatment; dengue virus ... See more keywords
Transcriptional and clonal characterization of B cell plasmablast diversity following primary and secondary natural DENV infection
Sign Up to like & getrecommendations! Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.102733
Abstract: Antibody-mediated humoral immunity is thought to play a central role in mediating the immunopathogenesis of acute DENV infection, but limited data are available on the diversity, specificity, and functionality of the antibody response at the… read more here.
Keywords: diversity; denv; primary secondary; secondary natural ... See more keywords
Brivanib alaninate inhibited dengue virus proliferation through VEGFR2/AMPK pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105721
Abstract: Dengue virus (DENV) is the most prevalent arthropod-borne viral disease of humans and has a major impact on global public health. There is no clinically approved drugs for DENV infection. Since intracellular VEGFR2 is increased… read more here.
Keywords: dengue virus; brivanib alaninate; infection; proliferation ... See more keywords
Vitamin D modulates inflammatory response of DENV-2-infected macrophages by inhibiting the expression of inflammatory-liked miRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2022.2101840
Abstract: ABSTRACT Dengue disease caused by dengue virus (DENV) infection is the most common vector-borne viral disease worldwide. Currently, no treatment is available to fight dengue symptoms. We and others have demonstrated the antiviral and immunomodulatory… read more here.
Keywords: denv infection; expression; expression inflammatory; mir ... See more keywords
Dengue Virus and Platelets: From the Biology to the Clinic.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0135
Abstract: Dengue is one of the most important vector-borne viral illnesses found in tropical and subtropical regions. Colombia has one of the highest rates of dengue cases in the Americas. Severe dengue virus (DENV) infection presents… read more here.
Keywords: denv infection; dengue virus; dengue; biology ... See more keywords
Vitamin D-induced LL-37 modulates innate immune responses of human primary macrophages during DENV-2 infection.
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens and disease"
DOI: 10.1093/femspd/ftac014
Abstract: Epidemics of dengue, an acute and potentially severe disease caused by mosquito-borne dengue virus (DENV), pose a major challenge to clinicians and health care services across the sub(tropics). Severe disease onset is associated with a… read more here.
Keywords: responses human; denv infection; infection; vitamin induced ... See more keywords
Comprehensive Evaluation of Differential Serodiagnosis between Zika and Dengue Viral Infections
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01506-18
Abstract: Diagnostic testing for Zika virus (ZIKV) or dengue virus (DENV) infection can be accomplished by a nucleic acid detection method; however, a negative result does not exclude infection due to the low virus titer during… read more here.
Keywords: infection; mac; zikv; denv infection ... See more keywords
Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules
Sign Up to like & getrecommendations! Published in 2017 at "mBio"
DOI: 10.1128/mbio.00741-17
Abstract: ABSTRACT Natural killer (NK) cells play a protective role against dengue virus (DENV) infection, but the cellular and molecular mechanisms are not fully understood. Using an optimized humanized mouse model, we show that human NK… read more here.
Keywords: adhesion molecules; infection; dendritic cells; denv infection ... See more keywords
Dengue virus infection induces inflammation and oxidative stress on the heart
Sign Up to like & getrecommendations! Published in 2021 at "Heart"
DOI: 10.1136/heartjnl-2020-318912
Abstract: Objective Dengue fever is one of the most important arboviral diseases in the world, and its severe forms are characterised by a broad spectrum of systemic and cardiovascular hallmarks. However, much remains to be elucidated… read more here.
Keywords: dengue virus; heart; oxidative stress; infection ... See more keywords