Molecular and genomic investigation of an urban outbreak of dengue virus serotype 2 in Angola, 2017–2019
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010255
Abstract: Background The transmission patterns and genetic diversity of dengue virus (DENV) circulating in Africa remain poorly understood. Circulation of the DENV serotype 1 (DENV1) in Angola was detected in 2013, while DENV serotype 2 (DENV2)… read more here.
Keywords: serotype; dengue; pcr; dengue virus ... See more keywords
Novel Aporphine- and Proaporphine–Clerodane Hybrids Identified from the Barks of Taiwanese Polyalthia longifolia (Sonn.) Thwaites var. pendula with Strong Anti-DENV2 Activity
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15101218
Abstract: Hybrid natural products produced via mixed biosynthetic pathways are unique and often surprise one with unexpected medicinal properties in addition to their fascinating structural complexity/diversity. In view of chemical structures, hybridization is a way of… read more here.
Keywords: taiwanese polyalthia; barks taiwanese; polyalthia longifolia; aporphine proaporphine ... See more keywords
Combination of E- and NS1-Derived DNA Vaccines: The Immune Response and Protection Elicited in Mice against DENV2
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DOI: 10.3390/v14071452
Abstract: The occurrence of dengue disease has increased radically in recent decades. Previously, we constructed the pE1D2 and pcTPANS1 DNA vaccines encoding the DENV2 envelope (E) and non-structural 1 (NS1) proteins, respectively. To decrease the number… read more here.
Keywords: protection; combination ns1; dna vaccines; ns1 derived ... See more keywords
Characterization of human anti-dengue NS1 monoclonal antibodies derived from Thai DENV2 patients.
Sign Up to like & getrecommendations! Published in 2021 at "Japanese journal of infectious diseases"
DOI: 10.7883/yoken.jjid.2020.1071
Abstract: Mouse antibodies specific to dengue NS1 have been widely studied for their cross-reactivity with several human molecules. This is the first cross-reactivity study of dengue NS1 specific human monoclonal antibodies (HuMAbs), isolated from DENV2 infected… read more here.
Keywords: denv2; dengue; monoclonal antibodies; cross reactivity ... See more keywords