LAUSR

Deorphanizing Peptides Using Structure Prediction

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2 Published in 2023 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.3c00378

Abstract: Many endogenous peptides rely on signaling pathways to exert their function, but identifying their cognate receptors remains a challenging problem. We investigate the use of AlphaFold-Multimer complex structure prediction together with transmembrane topology prediction for… read more here.

Keywords: using structure; peptides using; prediction; deorphanizing peptides ... See more keywords