Use of 18F‐2‐deoxy‐2‐fluoro‐D‐glucose positron emission tomography/computed tomography for staging thyroid carcinoma in a cat
Sign Up to like & getrecommendations! Published in 2023 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.1106
Abstract: Abstract Thyroid nodules are common in older cats and are mostly benign; however, carcinomas may occur infrequently. In cats, thyroid carcinomas tend to be highly metastatic. The role of 18F‐2‐deoxy‐2‐fluoro‐D‐glucose (FDG) positron emission tomography (PET)/computed… read more here.
Keywords: thyroid carcinoma; 18f deoxy; tomography; deoxy fluoro ... See more keywords
Synthesis and Structural Characterization of 2'-Deoxy-2'-fluoro-l-uridine Nucleic Acids.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01498
Abstract: Despite the development of artificial l-RNA/DNA as therapeutic molecules, the in-depth investigation on their chemical modifications is still limited. Here, we synthesize a chemically derivatized 2'-deoxy-2'-fluoro-l-uridine building block and incorporate it into oligonucleotides. Our thermo-denaturization… read more here.
Keywords: deoxy fluoro; synthesis structural; fluoro uridine; fluoro ... See more keywords
Phenanthroline-Catalyzed Stereoselective Formation of α-1,2-cis 2-Deoxy-2-Fluoro Glycosides.
Sign Up to like & getrecommendations! Published in 2021 at "ACS catalysis"
DOI: 10.1021/acscatal.0c04381
Abstract: Phenanthroline is a heterocyclic aromatic organic compound and commonly used in coordination chemistry acting as a bidentate ligand. The C4 and C7 positions of phenanthroline can often be substituted to change the binding capabilities of… read more here.
Keywords: chemistry; deoxy fluoro; formation cis;
Influence of nucleotide modifications at the C2’ position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx713
Abstract: Abstract Polyadenylate (poly(A)) has the ability to form a parallel duplex with Hoogsteen adenine:adenine base pairs at low pH or in the presence of ammonium ions. In order to evaluate the potential of this structural… read more here.
Keywords: ammonium ions; base; deoxy fluoro; poly ... See more keywords
Influence of fluorine substitution on the molecular conformation of 3'-deoxy-3'-fluoro-5-methyluridine.
Sign Up to like & getrecommendations! Published in 2020 at "Acta crystallographica. Section C, Structural chemistry"
DOI: 10.1107/s2053229620003083
Abstract: Fluorine substitutions on the furanose ring of nucleosides are known to strongly influence the conformational properties of oligonucleotides. In order to assess the effect of fluorine on the conformation of 3'-deoxy-3'-fluoro-5-methyluridine (RTF), C10H13FN2O5, we studied… read more here.
Keywords: conformation deoxy; deoxy fluoro; fluoro methyluridine;
9-(2′-Deoxy-2′-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02719-16
Abstract: ABSTRACT Current chemotherapy against African sleeping sickness, a disease caused by the protozoan parasite Trypanosoma brucei, is limited by toxicity, inefficacy, and drug resistance. Nucleoside analogues have been successfully used to cure T. brucei-infected mice,… read more here.
Keywords: drug resistance; deoxy fluoro; fluoro arabinofuranosyl; arabinofuranosyl adenine ... See more keywords