In Vitro and In Vivo Comparison of Gemcitabine and the Gemcitabine Analog 1-(2′-deoxy-2′-fluoroarabinofuranosyl) Cytosine (FAC) in Human Orthotopic and Genetically Modified Mouse Pancreatic Cancer Models
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DOI: 10.1007/s11307-017-1078-6
Abstract: PurposeAlthough gemcitabine is a mainstay of pancreatic cancer therapy, it is only moderately effective, and it would be desirable to measure drug uptake in patients. 1-(2′-deoxy-2′-fluoroarabinofuranosyl) cytosine (FAC), is an analog of gemcitabine, and when… read more here.
Keywords: fluoroarabinofuranosyl cytosine; gemcitabine; deoxy fluoroarabinofuranosyl; pancreatic cancer ... See more keywords