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Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03837-y
Abstract: PurposeSeveral retrospective studies have shown that the antitumor efficacy of capecitabine-containing chemotherapy decreases when co-administered with a proton pump inhibitor (PPI). Although a reduction in capecitabine absorption by PPIs was proposed as the underlying mechanism,…
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Keywords:
deoxy fluorouridine;
capecitabine;
fluorocytidine deoxy;
rabeprazole intake ... See more keywords