The conversion of l-lysine into l-β-lysine: the role of 5′-deoxyadenosyl radical and water—a DFT study
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DOI: 10.1007/s00894-020-04639-3
Abstract: In the current study, we deal with the crucial role of 5′-deoxyadenosyl radical and water in the mechanism of the conversion of l -lysine into l -β-lysine. The DFT (density functional theory)–B3LYP method coupled with… read more here.
Keywords: water; lysine; radical water; deoxyadenosyl radical ... See more keywords
The Elusive 5′-Deoxyadenosyl Radical: Captured and Characterized by Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopies
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DOI: 10.1021/jacs.9b05926
Abstract: The 5′-deoxyadenosyl radical (5′-dAdo·) abstracts a substrate H atom as the first step in radical-based transformations catalyzed by adenosylcobalamin-dependent and radical S-adenosyl-l-methionine (RS) enzymes. Notwithstanding its central biological role, 5′-dAdo· has eluded characterization despite efforts… read more here.
Keywords: electron; electron nuclear; deoxyadenosyl radical; paramagnetic resonance ... See more keywords