RNA-Mediated Dimerization of the Human Deoxycytidine Deaminase APOBEC3H Influences Enzyme Activity and Interaction with Nucleic Acids.
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DOI: 10.1016/j.jmb.2018.11.006
Abstract: Human APOBEC3H is a single-stranded (ss)DNA deoxycytidine deaminase that inhibits replication of retroelements and HIV-1 in CD4+ T cells. When aberrantly expressed in lung or breast tissue, APOBEC3H can contribute to cancer mutagenesis. These different… read more here.
Keywords: mediated dimerization; rna mediated; rna; deoxycytidine deaminase ... See more keywords