Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor®.
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.05.043
Abstract: Herein we disclose a deoxyfluorination of alcohols with an electrophilic fluorine source via visible-light photoredox catalysis. This radical-mediated C-F coupling is capable of fluorinating secondary and tertiary alcohols efficiently, complementing previously reported nucleophilic deoxyfluorination protocols. read more here.
Keywords: deoxyfluorination; alcohols selectfluor; catalyzed deoxyfluorination; deoxyfluorination activated ... See more keywords
Achievements in Fluorination Using Variable Reagents through Deoxyfluorination Reaction
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DOI: 10.1039/d1qo00952d
Abstract: The fusion of fluorine in drug molecules through different fluorinating reagents remains a cornerstone in pharmaceutical chemistry. Progress in the field of deoxyfluorination through the development of novel reagents has... read more here.
Keywords: using variable; achievements fluorination; variable reagents; chemistry ... See more keywords
Recent Developments in the Deoxyfluorination of Alcohols and Phenols: New Reagents, Mechanistic Insights, and Applications
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DOI: 10.1055/s-0036-1590881
Abstract: This short review describes the development of new reagents and methods for the deoxyfluorination of phenols and alcohols during the period of 2011 to 2017. Important advances in the mechanistic understanding of these processes are… read more here.
Keywords: recent developments; alcohols phenols; new reagents; developments deoxyfluorination ... See more keywords