Articles with "deoxyribonuclease" as a keyword



Repurposing of 8‐Hydroxyquinoline‐Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors

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Published in 2022 at "ChemMedChem"

DOI: 10.1002/cmdc.202100694

Abstract: A library of 31 butyrylcholinesterase (BChE) and cathepsin B (CatB) inhibitors was screened in vitro for inhibition of deoxyribonuclease I (DNase I). Compounds 22, 8 and 7 are among the most potent synthetic non‐peptide DNase I… read more here.

Keywords: deoxyribonuclease; dnase; cathepsin; repurposing hydroxyquinoline ... See more keywords