Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis
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DOI: 10.1111/imm.13569
Abstract: Multiple sclerosis (MS) is an autoimmune disease driven by lymphocyte activation against myelin autoantigens in the central nervous system leading to demyelination and neurodegeneration. The deoxyribonucleoside salvage pathway with the rate‐limiting enzyme deoxycytidine kinase (dCK)… read more here.
Keywords: dck; deoxycytidine kinase; deoxyribonucleoside salvage; multiple sclerosis ... See more keywords