Quantification of deoxythioguanosine in human DNA with LC-MS/MS, a marker for thiopurine therapy optimisation
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DOI: 10.1007/s00216-024-05581-6
Abstract: In the treatment of diseases such as acute childhood leukaemia (ALL) and inflammatory bowel disease (IBD), the thiopurines azathioprine, 6-mercaptopurine, and 6-thioguanine are used. Thiopurines are antimetabolites and immunomodulators used to maintain remission in patients.… read more here.
Keywords: deoxythioguanosine; deoxythioguanosine human; quantification deoxythioguanosine; dtg ... See more keywords