Gene therapy with helper-dependent adenoviral vectors: lessons from studies in large animal models
Sign Up to like & getrecommendations! Published in 2017 at "Virus Genes"
DOI: 10.1007/s11262-017-1471-x
Abstract: Helper-dependent adenoviral vectors (HDAd) are deleted of all viral genes and they can efficiently transduce a wide variety of dividing and non-dividing cells to mediate high transgene expression levels. Unlike early generation adenoviral vectors, the… read more here.
Keywords: large animal; gene therapy; adenoviral vectors; dependent adenoviral ... See more keywords