Characterization of the metallo-dependent amidohydrolases responsible for “auxiliary” leucinyl removal in the biosynthesis of 2,2′-bipyridine antibiotics
Sign Up to like & getrecommendations! Published in 2017 at "Synthetic and Systems Biotechnology"
DOI: 10.1016/j.synbio.2017.07.002
Abstract: 2,2′-Bipyridine (2,2′-BiPy) is an attractive core structure present in a number of biologically active natural products, including the structurally related antibiotics caerulomycins (CAEs) and collismycins (COLs). Their biosynthetic pathways share a similar key 2,2′-BiPy-l-leucine intermediate,… read more here.
Keywords: biosynthesis; dependent amidohydrolase; bipyridine; characterization metallo ... See more keywords