Rab9‐dependent autophagy is required for the IGF‐IIR triggering mitophagy to eliminate damaged mitochondria
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26346
Abstract: Mitochondria dysfunction is the major characteristic of mitophagy, which is essential in mitochondrial quality control. However, excessive mitophagy contributes to cell death in a number of diseases, including ischemic stroke and hepatotoxicity. Insulin‐like growth factor… read more here.
Keywords: iir; autophagy required; dependent autophagy; igf iir ... See more keywords
Inhibiting reactive oxygen species-dependent autophagy enhanced baicalein-induced apoptosis in oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-017-1076-7
Abstract: Autophagy modulation has been considered a potential therapeutic strategy for oral squamous cell carcinoma (OSCC). A previous study confirmed that baicalein might possess significant anti-carcinogenic activity. However, whether baicalein induces autophagy and its role in… read more here.
Keywords: baicalein; apoptosis; oral squamous; dependent autophagy ... See more keywords
Transcriptomic analysis of pathways associated with ITGAV/alpha(v) integrin-dependent autophagy in human B cells
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2113296
Abstract: ABSTRACT Macroautophagy/autophagy proteins have been linked with the development of immune-mediated diseases including lupus, but the mechanisms for this are unclear due to the complex roles of these proteins in multiple immune cell types. We… read more here.
Keywords: itgav alpha; alpha integrin; dependent autophagy; transcriptomic analysis ... See more keywords
Inhibiting MT2‐TFE3‐dependent autophagy enhances melatonin‐induced apoptosis in tongue squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12457
Abstract: Autophagy modulation is a potential therapeutic strategy for tongue squamous cell carcinoma (TSCC). Melatonin possesses significant anticarcinogenic activity. However, whether melatonin induces autophagy and its roles in cell death in TSCC are unclear. Herein, we… read more here.
Keywords: dependent autophagy; melatonin induced; melatonin; cell ... See more keywords
Isoflavones Induce BEX2-Dependent Autophagy to Prevent ATR-Induced Neurotoxicity in SH-SY5Y Cells
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000484075
Abstract: Background/Aims: Atrazine (ATR) is a broad-spectrum herbicide in wide use around the world. However, ATR is neurotoxic and can cause cell death in dopaminergic neurons, leading to neurodegenerative disorders. Autophagy is the basic cellular catabolic… read more here.
Keywords: atr; atr induced; bex2 dependent; dependent autophagy ... See more keywords
Metformin Promotes Beclin1-Dependent Autophagy to Inhibit the Progression of Gastric Cancer [Corrigendum]
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s266119
Abstract: [This corrects the article DOI: 10.2147/OTT.S242298.]. read more here.
Keywords: inhibit progression; autophagy inhibit; metformin promotes; dependent autophagy ... See more keywords
The phosphatidylinositol 3-phosphate effector FYVE3 regulates FYVE2-dependent autophagy in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1160162
Abstract: Phosphatidylinositol 3-phosphate (PI3P) is a signaling phospholipid that play a key role in endomembrane trafficking, specifically autophagy and endosomal trafficking. However, the mechanisms underlying the contribution of PI3P downstream effectors to plant autophagy remain unknown.… read more here.
Keywords: phosphatidylinositol phosphate; fyve2 dependent; arabidopsis thaliana; autophagy arabidopsis ... See more keywords
The Role of Beclin 1-Dependent Autophagy in Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Biology"
DOI: 10.3390/biology9010004
Abstract: Autophagy (self-eating) is an intracellular degradation process used by cells to keep a “clean house”; as it degrades abnormal or damaged proteins and organelles, it helps to fight infections and also provides energy in times… read more here.
Keywords: beclin dependent; dependent autophagy; role; autophagy ... See more keywords
Neuropeptide Y Promotes Human M2 Macrophage Polarization and Enhances p62/SQSTM1-Dependent Autophagy and NRF2 Activation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113009
Abstract: Neuropeptide Y (NPY) is an abundantly expressed peptide capable of modulating innate and adaptive immune responses and regulating chemotaxis and cytokine secretion by macrophages. Abnormal regulation of NPY is involved in the development of atherosclerosis.… read more here.
Keywords: p62 sqstm1; sqstm1 dependent; autophagy nrf2; macrophage ... See more keywords