The therapeutic potential of berberine chloride against SARM1‐dependent axon degeneration in acrylamide‐induced neuropathy
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DOI: 10.1002/ptr.7594
Abstract: Chronic acrylamide (ACR) intoxication causes typical pathology of axon degeneration. Moreover, sterile‐α and toll/interleukin 1 receptor motif‐containing protein 1 (SARM1), the central executioner of the programmed axonal destruction process under various insults, is up‐regulated in… read more here.
Keywords: dependent axon; sarm1 dependent; axon degeneration; berberine chloride ... See more keywords
APP Induces AICD-Mediated Autophagy-Dependent Axon Degeneration.
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DOI: 10.1111/acel.70301
Abstract: The amyloid precursor protein (APP) plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). While the production of Amyloid beta (Aβ) has traditionally been considered the primary cause of AD, the role of… read more here.
Keywords: autophagy dependent; app; degeneration; axon degeneration ... See more keywords