Residues important for K+ ion transport in the K+-dependent Na+-Ca2+ exchanger (NCKX2).
Sign Up to like & getrecommendations! Published in 2018 at "Cell calcium"
DOI: 10.1016/j.ceca.2018.06.005
Abstract: K+-dependent Na+-Ca2+ exchangers (NCKXs) play an important role in Ca2+ homeostasis in many tissues. NCKX proteins are bi-directional plasma membrane Ca2+-transporters which utilize the inward Na+ and outward K+ gradients to move Ca2+ ions into… read more here.
Keywords: transport; residues important; exchanger; ion ... See more keywords
Dopamine-mediated calcium channel regulation in synaptic suppression in L. stagnalis interneurons
Sign Up to like & getrecommendations! Published in 2018 at "Channels"
DOI: 10.1080/19336950.2018.1457897
Abstract: ABSTRACT D2 dopamine receptor-mediated suppression of synaptic transmission from interneurons plays a key role in neurobiological functions across species, ranging from respiration to memory formation. In this study, we investigated the mechanisms of D2 receptor-dependent… read more here.
Keywords: suppression; stagnalis; dopamine; voltage dependent ... See more keywords
Methyl-β-cyclodextrin modulates thapsigargin-induced store-dependent Ca2+ entry in macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672917020028
Abstract: Using Fura-2AM microfluorimetry, we have shown for the first time that preincubation of macrophages with methyl-β-cyclodextrin, inducing cholesterol extraction from membranes and raft disruption, leads to significant inhibition of thapsigargin-induced store-dependent Ca2+ entry in rat… read more here.
Keywords: store; store dependent; dependent ca2; ca2 entry ... See more keywords
FKBP52 regulates TRPC3-dependent Ca2+ signals and the hypertrophic growth of cardiomyocyte cultures
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Science"
DOI: 10.1242/jcs.231506
Abstract: ABSTRACT The transient receptor potential (TRP; C-classical, TRPC) channel TRPC3 allows a cation (Na+/Ca2+) influx that is favored by the stimulation of Gq protein-coupled receptors (GPCRs). An enhanced TRPC3 activity is related to adverse effects,… read more here.
Keywords: trpc3 dependent; dependent ca2; fkbp52; ca2 signals ... See more keywords
K+-Dependent Na+/Ca2+ Exchanger Isoform 2, Nckx2, Takes Part in the Neuroprotection Elicited by Ischemic Preconditioning in Brain Ischemia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137128
Abstract: Sodium/Calcium exchangers are neuronal plasma membrane antiporters which, by coupling Ca2+ and Na+ fluxes across neuronal membranes, play a relevant role in brain ischemia. The most brain-expressed isoform among the members of the K+-dependent Na+/Ca2+… read more here.
Keywords: neuroprotection; brain ischemia; brain; ischemic preconditioning ... See more keywords
Regulation of K+-Dependent Na+/Ca2+-Exchangers (NCKX)
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010598
Abstract: Potassium-dependent sodium-calcium exchangers (NCKX) have emerged as key determinants of calcium (Ca2+) signaling and homeostasis, especially in environments where ion concentrations undergo large changes, such as excitatory cells and transport epithelia. The regulation of NCKX… read more here.
Keywords: regulation dependent; nckx regulation; exchangers nckx; regulation ... See more keywords